The Mariners can do that with a fourth consecutive road victory over New York on Wednesday night.
Greeted by a chorus of boos, Cano struck out Tuesday in his first at-bat in New York since the former Yankees star signed a $240 million contract with Seattle (11-14) over the winter. Though Cano fanned twice in five at-bats, he also singled, had one RBI and scored a run during the Mariners' 6-3 victory.
Cano was able to block out the jeers, and claimed he never heard the chant of "You sold out!" from the "Bleacher Creatures" when he took his spot at second base.
"That's something I can't control," he said. "I'm not surprised. Just got to go out there and play my game."
Cano is batting .387 in his last eight games for Seattle, which has scored 26 runs while winning four of five following an eight-game skid during which it totaled 18.
"I've gotten used to not seeing him here, but then seeing him in another uniform because we don't play him in the spring is kind of an odd picture," said longtime double-play partner Derek Jeter, who is 1 for 9 in the last two games.
Catcher Mike Zunino had a career-high four hits after going 0 for 11 in his previous four games for the Mariners, who have batted .325 while outscoring the Yankees 21-7 during a three-game winning streak in the Bronx.
After veteran Chris Young allowed an earned run and three hits in 5 2-3 innings of the opener, Seattle rookie Roenis Elias (1-2, 3.54 ERA) will make his first appearance versus New York.
Boasting a 5.56 ERA while going 0-1 in his last two starts, the left-hander lasted 5 2-3 innings in each and gave up three runs during a 6-5 victory over Texas on Friday.
The Yankees counter with David Phelps (0-0, 3.86), who is filling the rotation spot of suspended ex-Mariner Michael Pineda. The right-hander is making his first start of the season after nine appearances out of the bullpen.
Phelps went 7-6 with a 4.39 ERA in 23 starts over the previous two seasons. That included a one-run effort over six innings while not factoring in the decision of a 2-1 win at Seattle last year.
According to manager Joe Girardi, Phelps is likely to be limited to 70-75 pitches.
Mark Teixeira homered in his second consecutive game Tuesday for New York, which opened this nine-game homestand by taking two of three from the Los Angeles Angels. Teixeira is 3 for 17 with six walks and six strikeouts in his last six contests, but each hit left the park.
It's uncertain if teammate Jacoby Ellsbury will be available after he missed Tuesday's game with a sore left hand.
"It's just been bothering him for a few days," Girardi told the Yankees' official website. "He's been playing through it."
A native of the Pacific Northwest, Ellsbury went 1 for 10 with four strikeouts in the Angels series but is batting .367 with two doubles and two home runs in his last seven games versus Seattle.