Odorizzi, who grabbed his groin/hamstring area, winced after throwing a warmup pitch, which brought Rays manager Kevin Cash and training personnel out of the dugout. Odorizzi appeared to try to stretch and then threw two warmup pitches, but was unable to continue and walked off the mound.
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Frazier missed two games with symptoms of the flu before returning Friday night as the designated hitter. Frazier was back at third base on Saturday but left after striking out in the fourth inning.
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Second baseman Brian Dozier of the Twins was out of the lineup against the White Sox after feeling some tightness and swelling in his right knee.
Minnesota's chief baseball officer, Derek Falvey, said an MRI exam on Dozier's knee did not show any significant injury.
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Holliday was hitless in four at-bats with three strikeouts against the Cardinals on Friday night.
He spent 7 1/2 seasons with St. Louis. He signed a one-year deal to be New York's regular designated hitter and is hitting .242 with one home run and five RBIs to go along with 10 walks.
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Home plate umpire Dale Scott was released from a Toronto hospital Saturday after being removed from the field on a stretcher in Friday night's game between the Blue Jays and Baltimore Orioles.
Scott, a 31-year veteran crew chief, was diagnosed with a concussion after a foul tip off the bat of Baltimore's Mark Trumbo hit him in the bottom part of his mask in the top of the eighth inning.
Scott, 57, staggered backward before going down on one knee after the ball knocked off his mask.
He was mobilized with a neck brace, placed on a stretcher and carted off the field.
(Editing by Gene Cherry)