Busch has six straight series victories dating to last season and 40 overall in 120 starts. The Sprint Cup driver led the final 55 laps in the 150-lap race. He also won at the 1.5-mile track in 2011.
''Really proud of Kyle Busch Motorsports finishing 1-2,'' Busch said. ''It's a great testament for everything we've gone for and strived for. ... Qualifying 1-2 and finishing 1-2, I think I was more pumped for having a 1-2 finish, than winning, honestly.''
Wallace, the winner two weeks ago at Gateway in Madison, Illinois, finished 1.844 seconds behind Busch.
Wallace shook his head sideways when asked if he thought he had a chance to beat Busch on a late restart.
''He knew what he was doing,'' Wallace said. ''He's so cool to work with. He's so good.''
Kyle Busch Motorsports drivers have won nine of the series' last 12 races, with Wallace winning twice and Erik Jones once. Toyota has won 10 straight races, starting with Jones' Phoenix victory last year.
''I'm really proud that my name is on the door,'' Busch said. ''I'm most proud of Eric Phillips (crew chief) and all the guys, everyone at Kyle Busch Motorsports for all their hard work and dedication and everything they've done to build really good trucks. They've done a great job for me.
''Seeing Darrell come home second tonight was pretty great, especially him getting back in traffic, like we both were and being able to methodically work his way back up to second.''
Ryan Blaney was third, followed by Timothy Peters, Brad Keselowski, Matt Crafton, Austin Dillon, Ron Hornaday Jr., points leader Johnny Sauter and Ben Kennedy.
Sauter has an eight-point lead over ThorSport Racing teammate Crafton, the defending series champion and a two-time winner this season.