OXFORD, Miss. -- Kentucky's Kyle Wiltjer came off the bench to score a career-high 26 points, and the Wildcats beat No. 16 Mississippi 87-74 Tuesday at C.M. "Tad" Smith Coliseum.
The Wildcats (14-6, 5-2) earned their third SEC road win of the season, their second victory in a row overall.
The Rebels (17-3, 6-1) saw their nine-game winning streak end while losing a conference game for the first time. They fell to 11-1 at home this season.
The Wildcats erased 38-37 halftime deficit by outscoring the Rebels 36-18 the first 10 minutes of the second half. Kentucky led 73-56 with 10:16 to go thanks to the big run.
The Rebels didn't go down without a fight, however, as they climbed back within 73-72 with 4:25 left on a 3-pointer from LaDarius White, who scored a team-high 22 points.
Kentucky finished the game strong, though, outscoring the Rebels 14-2 the rest of the way.
Archie Goodwin scored 24 points and Alex Poythress had 15 for Kentucky. Center Nerlens Noel had a school-record 12 blocked shots, plus seven rebounds and two points.
Marshall Henderson added 22 points for the Rebels, who also got 10 points apiece from Jarvis Summers and Murphy Holloway.
Kentucky shot 50 percent (28-for-56) from the floor, while Ole Miss made just 32.9 percent of its shots (28-for-85).
Ole Miss took a 38-37 halftime lead, with Henderson scoring a team-high 16 points before the break.
White had 15 first-half points for the Rebels. Kentucky, which was coming off a 75-70 win over LSU, got 17 points from Wiltjer prior to intermission.
A total of 26 fouls were called in the first half, with the Rebels leading the way with 14. Ole Miss scored nine of its points at the line, while Kentucky's defensive stopper, Noel, had five blocks.
Ole Miss' biggest lead of the first half was 28-22 with 4:56 left. Kentucky never led by more than two points.
NOTES: This was the first time since 2001 the Rebels entered a matchup with Kentucky when the Wildcats were unranked. That year, the No. 21 Rebels beat the Wildcats 65-55 at home. ... Holloway, a senior forward, became the school's all-time leading rebounder by grabbing eight rebounds in the contest. Walter Actwood's old mark was 945 boards.