The Jacksonville Jaguars placed running back Jalen Parmele (groin) and cornerback William Middleton (concussion) on season-ending injured reserve and released wide receiver Micheal Spurlock safety Chris Harris.
Cornerback Antwaun Molden and wide receiver Quan Cosby were signed to the 53-man roster, running back Jordan Todman was signed off the Minnesota Vikings' practice squad and wide receiver Toney Clemons was signed off the Pittsburgh Steelers' practice squad.
Defensive end Ryan Davis was signed to the Jaguars' practice squad.
Parmele had been assuming a larger workload in the backfield with Maurice Jones-Drew still sidelined by a foot injury, but was injured during Sunday's 24-19 victory over the Tennessee Titans. He finishes the season with 143 yards on 40 carries. Rashad Jennings will again become the primary ballcarrier until Jones-Drew returns, with Todman likely to see action as well.
Middleton, a fourth-year player, started three of 10 games this season and finishes with 20 tackles and a pass defensed.
Spurlock is tied for sixth on the Jaguars with 14 receptions this season, and has also return six punts and six kickoffs.
Harris is an eighth-year veteran who saw action in only five games this season, producing one tackle.
Molden was a third-round pick of the Houston Texans in 2008 and has played in 48 career NFL games. Cosby was originally signed by the Cincinnati Bengals as an undrafted rookie in 2009 and has played in 42 career games while spending time with the Denver Broncos and Indianapolis Colts as well.
Todman was a sixth-round pick by the San Diego Chargers in 2011, but has yet to have an NFL carry. Clemons was a seventh-round pick by the Steelers in April and spent the first 12 weeks of his rookie season on their practice squad.