The Indians announced manager Manny Acta was fired with six games remaining in the 2012 season.
He'll be replaced on an interim basis by Sandy Alomar.
Acta compiled a record of 214-266 (.446) over his three seasons after being named manager on October 25, 2009. Acta previously managed the Washington Nationals but was fired at midseason and replaced by Jim Riggleman.
"The Cleveland Indians would like to thank Manny Acta for everything he has done for the organization in his three seasons as our manager," said Chris Antonetti, executive vice president and general manager, in a team-issued statement. "Manny's passion for the game, positive attitude and tremendous knowledge of baseball helped guide us to a number of high points during his tenure. Managerial changes are never easy or taken lightly, but as we approached the end of the season and turned our attention to assessing the year, we determined a change was necessary."
Alomar is a candidate for the manager's job and a search for a permanent manager is underway, the Indians announced.
The 46-year-old has been a member of the coaching staff since 2010 and was bench coach last season.
"I fully support Chris' decision to make this change and am confident that he will lead a tireless search to find the right individual to lead the club to our ultimate goal of winning the World Series," Indians chairman Paul Dolan said.