The San Francisco Giants have never won three straight games in Oakland.
Matt Cain could change that.
Cain will try to become the first Giants pitcher in 60 years to win nine consecutive starts Sunday when the Bay Bridge Series concludes.
Limited to six runs while losing six straight in Oakland prior to this series, San Francisco (40-32) has scored 14 total runs in the last two contests to clinch the season series.
After rallying with four ninth-inning runs in Friday's 5-4 victory, the Giants hung on for a 9-8 victory Saturday after the A's scored four in the ninth.
"To come away with a win when you're on the ropes like that, it's big,'' manager Bruce Bochy said. "This would have been hard to take.''
San Francisco finishes its nine-game trip - and goes for its first sweep in Oakland since a two-game set June 22-23, 1998 - with Cain (9-2, 2.34 ERA) trying to become the franchise's first pitcher to win nine straight starts since Sal Maglie from April 16-May 27, 1952, when the team was based in New York.
One start removed from throwing baseball's 22nd perfect game, Cain was far from perfect in a 5-3 road win over the Los Angeles Angels on Monday when he walked a season-high four and surrendered three runs in five innings.
"I'd say it was a gutty effort,'' Bochy said after Cain became the team's first pitcher since Rick Reuschel in 1989 to win eight consecutive starts. "I'm sure he felt the residuals from his last start. He had to. .... He's relentless out there. He just keeps grinding, and he got a win out of it.''
Since throwing a one-hitter in a 6-0 victory May 21, 2006, Cain is 0-2 with a 1.69 ERA in his last three starts in Oakland (34-38), with the Giants scoring three total runs during those contests.
San Francisco has averaged 5.8 runs during Cain's current winning streak.
Right-hander Brandon McCarthy was slated to start the series finale for Oakland, but he has been scratched due to recurring shoulder soreness.
"It seems like the last two weeks have been as mentally harrowing as I've had to deal with in my career,'' he said. "I feel miserable. I'm obsessing over the pain. I feel like I've done everything I could do but there are so few answers right now. The frustration level has gone off the charts.''
Instead of trying to stop McCarthy from winning his seventh straight decision, the Giants will now face A.J. Griffin in his major league debut.
The right-hander, a 13th-round pick out of the University of San Diego in 2010, went 3-2 with a 2.81 ERA at Triple-A Sacramento this season.
Griffin should be careful pitching to first baseman Brandon Belt, who is 3 for 5 with a home run and five RBIs in this series and is batting .441 (15 for 34) with four homers and 12 RBIs during a career-best 11-game hitting streak.
"It's more a feel for me,'' Belt said. "It's been a lot of hard work in the cage.''
A's outfielder Josh Reddick has homered in three straight games against the Giants. He hit a two-run shot in a 6-2 victory May 20 that helped Oakland salvage the finale of a three-game set at San Francisco.
Reddick has never faced Cain.