Coach Anthony Lynn said Thursday that the team will be cautious before bringing the third-year lineman back. Bosa first injured the foot during training camp, which caused him to miss the preseason. He then reinjured it during practice on Sept. 5.
Bosa has 23 career sacks in two seasons, including an NFL-record 19 in his first 20 games. His presence was missed in last week's 38-28 loss to Kansas City as the Chargers were unable to consistently pressure Pat Mahomes and only got one sack.
The Chargers will be facing another elusive quarterback in Bills rookie Josh Allen, who will be making his first NFL start.
Isaac Rochell is expected to get the start again in Bosa's place.
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