Greinke looks to get the Dodgers on track when they open this four-game series with the host Colorado Rockies on Thursday night.
Greinke (10-4, 2.78 ERA) is among the major league leaders in wins, and he's been especially critical for Los Angeles (48-39) following losses. He's gone 13-2 with a 1.98 ERA in 19 starts following a Dodgers defeat since joining them in December 2012.
Greinke has a chance to improve that gaudy record after Los Angeles fell 5-4 to Cleveland on Wednesday, its second consecutive loss.
He won his latest start under the same circumstances, following Friday's 3-1 defeat to St. Louis by allowing one run and four hits with 10 strikeouts in seven innings of a 9-1 victory over the Cardinals the next day.
The performance was an improvement after Greinke gave up season highs of five runs and 11 hits in 5 2-3 innings of a 5-3 loss at Kansas City on June 23.
He's 0-2 with a 4.18 ERA in his last four road starts, one of which came at Coors on June 7 in which he allowed four runs and 11 hits in seven innings of a 5-4, 10-inning defeat.
Greinke has gone 1-0 with a 6.23 ERA in three starts at Colorado as a Dodger. However, he could be poised for a better performance at Denver as the Rockies are in a 2-14 tailspin that started with them being swept in three games at Los Angeles from June 16-18.
Greinke won the middle game of that series, yielding one run in six innings. Colorado, though, has a .326 average at home and has batted .308 in its last six there despite going 1-5.
The problem has been the pitching, with the Rockies posting a 7.00 ERA - 8.07 from the starters - in that stretch. Their 4.98 overall ERA is the worst in the majors, and they compiled a 6.75 mark while being swept in a three-game series at Washington, dropping the finale 4-3 on Wednesday.
Colorado has used 12 starters, most in the majors, and it's returning to Franklin Morales (4-4, 5.75) with Jhoulys Chacin going on the disabled list Monday with right shoulder inflammation. An MRI indicated Chacin may be out for awhile, and he started the year on the DL with a shoulder injury.
"It looks like he has some (rotator) cuff inflammation and we need to sit down with the medical staff and figure out a plan of attack," manager Walt Weiss said.
Morales opened the season in the rotation, but went 3-4 with a 6.13 ERA in 11 starts. He surrendered 11 runs and five homers in 10 innings over his last two starts - the latest May 31 - before being moved to the bullpen.
The left-hander has posted a 4.50 ERA and given up four homers in eight ensuing relief appearances. However, that stretch includes three scoreless innings over two meetings with the Dodgers, earning the win June 7.
The Rockies have been outscored 24-4 while losing four matchups since.