Coming off a successful home opener, the Giants try for a fourth consecutive victory over the Diamondbacks on Wednesday night.
San Francisco (6-2) took three of four at Arizona to open its season before winning two of three at Dodger Stadium. The Giants then got a two-run homer from Brandon Belt and a solid eight innings from Tim Hudson in Tuesday's 7-3 win over the Diamondbacks (2-8).
The Giants have scored 30 runs and recorded 18 extra-base hits, including seven home runs, in the five games versus Arizona.
Four of Belt's five home runs and all but two of his nine RBIs have come against the Diamondbacks. Teammate Angel Pagan added two more hits Tuesday to raise his average to .441 overall and .455 (10 for 22) versus Arizona this year.
The Diamondbacks went 1 for 5 with runners in scoring position and are 16 for 85 (.188) on the season.
"We had our chances," manager Kirk Gibson said. "We weren't able to hold them down. We weren't able to get the big two-out hits like they did."
Tim Lincecum (0-0, 6.00 ERA) makes his second straight start against Arizona after yielding two-run homers to Paul Goldschmidt and Mark Trumbo in Thursday's 8-5 win. The right-hander struck out seven and walked none in six innings.
Goldschmidt, batting .385 overall and .381 (8 for 21) against the Giants this season, is 12 for 23 with six home runs versus Lincecum.
"I'm going to start throwing underhand to him or something," Lincecum told the Giants' official website. "It's a game of adjustments. He's constantly making them against me, so I've got to do the same thing against him. That will be for the next go-around."
Lincecum has received four runs of support while going 0-4 with a 4.35 ERA in his last five home starts against the Diamondbacks. He'll again oppose veteran right-hander Bronson Arroyo (0-0, 4.15).
Though back problems plagued Arroyo during spring training, he was able to open the season and allowed two runs and five hits in 4 1-3 innings Thursday in his Arizona debut.
"I felt good, as good as I could have asked for," Arroyo told the Diamondbacks' official website. "It's a long season, that's what it is. You try to chew up as many (innings) as you can. If you consistently do that, then you've done your job. And if you get knocked out like I did before you can even finish five, then you haven't."
After going 0-4 with a 4.11 ERA in his first six starts at San Francisco, Arroyo put together a one-hit, seven-inning performance in a 9-0 victory for Cincinnati in Game 2 of the 2012 NL division series. Then last season, he tossed a seven-hitter and struck out six without a walk in an 11-0 win there.
Belt, the first Giant since Jose Cruz Jr. in 2003 to hit five home runs in the first eight games, is 5 for 9 with two homers against Arroyo in the regular season.