Billy Garrett Jr. and Durrell McDonald had 15 points apiece and Sandi Marcius added 10 as the Blue Demons (11-18, 3-13 Big East) won for the first time since Jan. 14, a 77-75 victory against St. John's, with all the losses coming in-conference.
Fuquan Edwin had a game-high 21 points to lead Seton Hall (14-14, 5-10). Edwin, though, was hampered by a sprained thumb in the second half and didn't score in the final 13 minutes of the game. He left the game briefly midway through the second half and missed his only two field-goal attempts after returning. Edwin has led the Pirates in scoring in four straight games.
The game was decided at the line, where DePaul went 17 of 18 and Seton Hall made just 5 of 11.
Seton Hall posted an 86-69 victory in the first meeting between the teams Jan. 25 at the Prudential Center in Newark, N.J.
DePaul committed turnovers on two of its first three possessions and fell behind 7-2 early in the game. It appeared it might be another long night, but the Blue Demons responded with a 14-4 run to take a 16-11.
For the season, DePaul entered the game shooting 40.9 percent from the field, but was locked in during the first half. The Blue Demons were 15-for-21 (71.4 percent) from the field in the first half, including four of eight from three-point range. The hot-shooting helped them to a 38-29 halftime lead despite 10 turnovers in the first 20 minutes.
Seton Hall opened the second half with a 13-4 run to tie the score at 42 with just over 15 minutes left. After a pair of free throws by Garrett put DePaul back on top, the Pirates ran off eight straight points for a 50-44 lead with just under 13 minutes to go.
But instead of folding, the Blue Demons rallied and scored eight straight to reclaim a 52-50 advantage. The game was tight down the stretch before DePaul ended with a 9-2 spurt.
With the score tied at 58 with just under three minutes left, McDonald hit a long three-pointer as the shot clock expired to give DePaul a 61-58 edge. A little than a minute later, Young had a steal and a fast break layup to make it 63-58 with 1:29 to go. He added the game's final points on a pair of free throws with 12.7 seconds to go.