OMAHA, Neb. (AP) -- Doug McDermott and Will Artino scored 14 points apiece to lead five Creighton players in double figures, and the Bluejays stayed alone in first place in the Big East with a 76-63 victory over Georgetown on Saturday night.
Ethan Wragge scored all 12 of his points in the first half, Devin Brooks had 11 and Jahenns Manigat added 10 for the Bluejays (17-3, 7-1).
Artino, a 6-foot-11 reserve center, had a career high for points on a night he played extended minutes in place of Wragge, who sat out much of the second half in foul trouble.
Markel Starks had 21 points for the Hoyas (11-8, 3-5), who have lost four straight and five of their last six. D'Vauntes Smith-Rivera had 18 points and Mikael Hopkins 14 for Georgetown.
Creighton has won 11 of its last 12 and extended its home win streak to 13 games in front of a school-record crowd of 18,859 on Pink-Out Night at the CenturyLink Center.
Georgetown shot 39 percent, its third straight game it has failed to crack 40 percent from the floor.
The Hoyas played their fifth straight game without starting guard Jabril Trawick, who broke his jaw Jan. 8. The Hoyas also were without 6-foot-11, 350-pound center Joshua Smith, who on Friday was declared academically ineligible for the rest of the season.
Creighton led by 10 points at halftime, and Georgetown had an opportunity to come back with McDermott having an off shooting night and Wragge going to the bench with three fouls early in the second half.
The Bluejays got a couple big plays from Artino after the Hoyas cut it to 42-36. Artino cut through the lane for a dunk putback of Austin Chatman's missed layup, and after a Georgetown turnover, he scored to make it a 10-point game again.
McDermott and Manigat finished a 10-0 run that gave Creighton a 58-40 lead. McDermott missed a 3-pointer, ran down the long rebound in the corner and on the same possession put back his own missed layup. Manigat followed a Georgetown turnover with a long 3-pointer.
The Bluejays, who couldn't seem to miss in their 96-68 victory at Villanova on Monday, struggled at the start against the Hoyas. They missed 12 of their first 15 shots, but it didn't hurt them because Georgetown was off on 11 of its first 13. The Bluejays finished at 46 percent.
Wragge, who made a school record-tying nine of Creighton's Big East-record 21 3-pointers against Villanova, also took a while to get going. His first 3-point try was blocked by Nate Lubick, and his second one nicked the front of the rim. Wragge made his next three, though, and his teammates started to warm up along with him.
Chatman tipped in his own miss to start an 11-0 run that put Creighton ahead 24-15, and the Bluejays made 7 of their last 10 shots of the half to lead 34-24.
The game started a difficult stretch for the struggling Hoyas. They play fourth-ranked Villanova at home on Monday and Michigan State at Madison Square Garden in New York on Saturday.
Creighton wore special pink-and-white jerseys and pink shoes as part of Creighton vs. Cancer weekend. The jerseys brought in about $48,000 in an auction, more than the previous two years combined. McDermott's No. 3 jersey fetched the most, $11,603. The first 16,000 fans through the doors received a pink T-shirt.