NORMAN, Okla. (AP) -- After the first overtime game in the Bedlam rivalry, a wild celebration on Owen Field and yet another 500-yard passing game, it all settled in for Landry Jones.
His last home game with Oklahoma was over, and what a way to go out.
Jones threw three touchdown passes and Brennan Clay scored on an 18-yard run in overtime to lift the 14th-ranked Sooners to a 51-48 win against No. 22 Oklahoma State in the Bedlam rivalry on Saturday.
''No better way,'' Jones said. ''God blessed me so much tonight to be able to go out like this.
''There's no better way to go out.''
The Sooners (9-2, 7-1 Big 12) never led during regulation, wiping out double-digit deficits in both halves. Backup quarterback Blake Bell tied it with 4 seconds left on a 4-yard keeper on fourth-and-1 after Jones directed the first 16 plays of an extended drive.
The victory kept alive Oklahoma's chances for at least a share of the Big 12 championship. The Sooners could win it outright by beating TCU next week if No. 7 Kansas State loses to Texas.
''Football's a crazy game,'' Jones said. ''There's up sand downs, good and bad. You have to stay somewhere in that middle ground, realizing who you are and what you're capable of and what type of offense you are.
''When you need a play, just go out and make it.''
On the Sooners' second play, Clay got through traffic at the line of scrimmage and then broke through attempted tackles by Daytawion Lowe and Shamiel Gary to score the game-winner and set off an unusually giddy celebration on Owen Field.
The Sooners had lost only three times at home in Bob Stoops' first 13 seasons but dropped games this season against Kansas State and Notre Dame.
Players ran around the field in celebration, joining fans in the stands in leaping up and down when ''Jump Around'' was blared over the loudspeaker.
''It always feels great to go out on a win,'' Jones said.
Joseph Randle ran for 113 yards and matched his career-high with four touchdowns for Oklahoma State (7-4, 5-3), which settled for Quinn Sharp's 26-yard field goal in overtime.
Last season, the Cowboys blew out Oklahoma 44-10 to snap an eight-game losing streak in the series and win their first Big 12 championship outright.
Oklahoma State fans rushed the field and tore down the goalposts after that win. A year later, the elation was replaced with disappointment.
''The truth is the better your program gets, the more success you have and the more highly regarded you are, the harder it is to lose,'' coach Mike Gundy said.
''In a World Series, a Super Bowl or a state championship game when you lose it's a crushing blow. And the only reason is because you've taken it to another level. For the most part, this program's at a different level.''
With his second straight 500-yard passing game, Jones surpassed Texas Tech's Graham Harrell to become the Big 12's career passing leader. He also became the first Bowl Subdivision quarterback ever to throw for 3,000 yards and 26 touchdowns in four seasons.
He led Oklahoma's first fourth-quarter comeback victory in five years a week earlier, beating West Virginia 50-49 on a pass to Kenny Stills with 24 seconds left.
''What more do you want from the guy? The guy was, again, fabulous out there tonight,'' Sooners coach Bob Stoops said. ''He threw the ball all over. He threw it well, throwing bullets everywhere.''
Jones finished 46 of 71, both school records, with an interception.
Clint Chelf threw for 240 yards and a touchdown and also ran for 63 yards for the Cowboys, who were trying to win on Owen Field for only the ninth time but couldn't protect an early 14-0 lead or an 11-point edge in the second half.
''There were a lot of big plays. You know there's going to be ups and downs throughout the game, so we were prepared for that,'' Chelf said. ''We just tried to answer every time they did something and they just made one more play than us.''
Jalen Saunders tied it at 38 on the second play of the fourth quarter, dodging three early tackles and racing 81 yards up the Sooners' sideline to score on a punt return.
Oklahoma State answered two possessions later, going 77 yards and taking a 45-38 lead on J.W. Walsh's 2-yard keeper with 10:41 remaining. The Cowboys sacked Jones on third down and forced an incomplete pass on fourth down to get the ball back with 7:07 to play, but went three-and-out to give it right back and set up Oklahoma's tying drive.
''We're strong,'' Clay said. ''We're strong-willed and we can face adversity. We can go through any obstacle, and we know this offense is very potent.''