Marvin Chavez marked his return to Colorado by helping Chivas USA end an 11-match winless streak against the Rapids earlier this year.
The Rapids are seeking revenge on a special night for their coach.
Pablo Mastroeni will be inducted into the club's Gallery of Honor on Friday night, when his Rapids will likely be without top goal scorer Deshorn Brown for a rematch with Chavez and Chivas.
Chivas USA (6-8-5) ended an 0-8-3 slide against Colorado with a 3-1 road victory May 11. Chavez scored twice off the bench in his club debut after playing twice this year for the Rapids.
Coach Wilmer Cabrera's club also ended a 0-4-2 slide in Colorado in which it was outscored 16-3.
"Now we know that we can win over there," Cabrera told Chivas' official website. "If you know that you can win in a special venue, with high altitude, you cannot be afraid of anything anymore."
The match was played on a snow-covered field. Erick Torres, whose 14 goals are tied for second in the league with Sporting Kansas City's Dom Dwyer, had the other Chivas score on an assist from another former Rapids player, Martin Rivero.
"It was a strange game, I think it was Mother's Day and it was snowing and they just hit us on the counter-attack a couple of times off our giveaways," said Colorado goalkeeper Clint Irwin, whose team held a 16-6 edge in overall shots. "I think we're more prepared for that this time and we'll be ready to go Friday."
The Rapids (7-6-6) are honoring Mastroeni, the club's all-time leader in games and former long-time captain. He becomes the fifth person to be inducted into Colorado's Gallery of Honor.
"We know it's a special night for Pablo and a special night for the club so we have got to do our part to get the win for the fans and for Pablo," Irwin said.
It doesn't look like Mastroeni will have Brown, who leads the team with seven goals including one in the last meeting. Brown is questionable due to a right groin strain suffered in last Friday's 2-1 loss at Portland in which he scored the Rapids' goal.
Gabriel Torres, who has yet to score this year, could take his place in the lineup.
"If Deshorn's not available, I think we have a guy stepping up in Gabby Torres that's definitely going to be a threat around goal," midfielder Dillon Serna said.
Colorado will have a trio of players back from suspension in forward Vicente Sanchez and midfielders Nick LaBrocca and Shane O'Neill. Sanchez is second on the team with six goals in seven matches and did not face Chivas in May due to a sprained left knee.
Chivas had a four-game win streak snapped Sunday with a 3-1 defeat at D.C. United. Torres converted a penalty kick in the 84th minute after his team was down by three goals.
These clubs swapped midfielders July 1 with Colorado sending Nathan Sturgis to Chivas for Carlos Alvarez. Sturgis has made four appearances as a Chivas reserve while Alvarez started last Friday in his second appearance for the Rapids.