The team said Friday that Price will not play Saturday night in Ottawa after missing a 4-1 victory in Buffalo on Thursday night in the opener.
A Tweet from the club said: ''Medical update: C. Price: severe case of flu, accompanied by fever, is taking antibiotics, resting at home, evaluated daily by Dr. (David) Mulder.''
Price has not played for Montreal since he injured a knee last Nov. 25, but returned in full health to help Canada win the World Cup of Hockey in September. Al Montoya was expected to make a second start in goal, with Charlie Lindgren as backup.
The Canadiens will have defenseman Jeff Petry back from an injury.