Jose Quintana will get another start in place of the injured John Danks, and the Chicago White Sox are hoping his next outing goes a little more smoothly.
The return of Paul Konerko also could provide a boost in helping end a minor slump.
Chicago looks to bounce back from only its third loss in 17 games Wednesday night when it hosts the Toronto Blue Jays.
The AL Central-leading White Sox (31-24) won 13 of 14 from May 17-June 1, posting a nine-game winning streak to complete that run. However, they've since lost two of three, including a 9-5 defeat in the series opener Tuesday.
Konerko missed his second straight game after having a chip in his left wrist removed in a minor procedure. Konerko, who leads the majors hitting .366 but is 1 for 16 over his last four games, should be ready to play Wednesday.
"Yeah, your body always feels better," Konerko told the team's official website about getting some extra rest. "It gets to cool down for a couple of days."
Danks, though, remains on the disabled list due to a left shoulder strain, and manager Robin Ventura will give Quintana (1-0, 1.69 ERA) the nod again after an unexpected and controversial ending to his start last Wednesday at Tampa Bay.
The rookie threw behind Ben Zobrist in an apparent retaliation after three White Sox batters were either hit or close to being hit with pitches. Quintana was ejected without warning after allowing one hit - a solo homer - in 3 2-3 innings, and Ventura also received his first managerial ejection.
"I definitely was surprised by it," Quintana said. "I wasn't expecting it."
The left-hander gave up two runs in six innings to beat Cleveland on May 25 in his first major league start. He's also pitched 6 1-3 scoreless innings over two relief appearances, recording two outs on three pitches Saturday against Seattle.
Chicago, the majors' only division leader with a sub-.500 record at home (14-15), hopes Quintana can cool off Toronto's Colby Rasmus, who went 5 for 5 with a homer and three RBIs Tuesday.
Rasmus is hitting .362 with four homers over his last 11 games.
"I like hitting in the two-hole. It doesn't give you a lot of time to think," Rasmus said. "The game starts and you're in there hitting. The at-bats come real fast and there's not a lot of sitting around, which is good."
Having won five of its last seven, Toronto (29-26) will send the unpredictable Brandon Morrow to the mound Wednesday.
Despite being one of only two major league pitchers along with Johan Santana to throw multiple shutouts, Morrow (6-3, 3.28) has been inconsistent. He went 0-1 with a 4.50 ERA in his first three starts, then won four straight outings with a 0.65 ERA from April 23-May 9.
The right-hander has been up and down since. He gave up six runs in a loss to Tampa Bay on May 14, then beat the New York Mets with a three-hit shutout May 19 before lasting only two-thirds of an inning while giving up six runs in a loss to Texas on May 25.
Morrow, who is 0-1 with a 4.76 ERA in four career starts versus the White Sox, struck out eight in 6 1-3 innings of a 4-1 win over Baltimore last Wednesday.
The Blue Jays have won six of nine in Chicago.