TORONTO -- Edwin Encarnacion hit a two-run homer, and Todd Redmond pitched into the sixth inning as the Toronto Blue Jays defeated the New York Yankees 7-2 Wednesday.
Brett Lawrie added a two-run double for the Blue Jays, who scored four runs in the first inning before a crowd of 36,565 at Rogers Centre.
Toronto won the rubber match of the three-game series to improve to 3-13 on the season against the Yankees. There are three games left between the American League East rivals.
Redmond (2-2) held the Yankees to three hits, four walks and two runs while striking out seven in 5 2/3 innings. He earned his first win since July 7, his second in the major leagues. Redmond went 0-1 in his next seven starts before Wednesday's win.
Aaron Loup, Sergio Santos and Darren Oliver held the Yankees to two hits the rest of the way.
Right-hander Hiroki Kuroda (11-10) allowed nine hits and seven runs (five earned) in five innings, taking his third loss in a row. He is 1-4 in his past five starts.
Mark Reynolds had three hits and an RBI for the Yankees.
In the first inning, Toronto's Ryan Goins doubled to give him a hit in each of his first six major league games. Adam Lind walked and Lawrie doubled both runners home. Rajai Davis was hit by a pitch.
J.P. Arencibia looked at a third strike, but the ball bounced off the glove of catcher Chris Stewart for a passed ball. As Arencibia ran to first, Stewart's throw hit him. Lawrie and Davis scored on the error.
Toronto increased the lead to 6-0 in the second when Encarnacion hit his 34th home run of the season after Goins singled.
The Blue Jays led 7-0 in the third after singles by Arencibia and Anthony Gose and a sacrifice fly by Jose Reyes.
The Yankees scored two in the fourth on two walks, a single by Alex Rodriguez and a double by Reynolds. Rodriguez was out trying to score on Reynolds' hit.
NOTES: Yankees 2B Eduardo Nunez (right knee) was a late scratch, and Reynolds took his place. ... New York 2B Robinson Cano (left hand bruise) sat out after being hit by a pitch in Tuesday's game. ... Blue Jays RHP Steve Delabar (right shoulder inflammation) pitched one perfect inning in the rookie-level Gulf Coast League on Wednesday to start his rehab assignment. ... Both teams have Thursday off. The Blue Jays open a three-game home series against Kansas City on Friday, sending out LHP Mark Buehrle (10-7, 4.08 ERA) against RHP Ervin Santana (8-7, 3.21). The Yankees open a three-game home series against Baltimore on Friday, with LHP CC Sabathia (11-11, 4.81) starting against RHP Miguel Gonzalez (8-6, 3.77).