The winless New York Giants fell to 0-6 as Eli Manning was intercepted three times during a 27-21 loss to the New York Giants.
Bears quarterback Jay Cutler threw two touchdown passes to wide receiver Brandon Marshall on Thursday night in Chicago.
The Bears are now 4-2 after losing their previous two games.
The Giants haven't been 0-6 since 1976.
"We're all sick of it," coach Tom Coughlin said. "We're all sick of losing, but we put ourselves in this position. There is only one way to get out of it."
Cutler was 24 of 36 for 262 yards as Marshall caught nine passes for 87 yards.
"We won the game, but we kind of leave a little bit unsatisfied because I think offensively we could have exploded for a little bit more," Cutler said.
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Aaron Wilson covers the Ravens for The Baltimore Sun.