LANDOVER, Md. (AP) -- With Adam Snyder starting for inactive left guard Mike Iupati, the 49ers are using a juggled offensive line for the first time since the 2011 season.
San Francisco used the same five starting offensive linemen for the previous 29 games.
Iupati is out Monday night against the Redskins after spraining a ligament in his left knee a week ago. It's the only start he's missed since entering the NFL in 2010.
The 49ers' defense is without cornerback Tarell Brown, inactive with a rib injury.
Redskins fullback Darrel Young is inactive because of a hamstring injury, and defensive lineman Stephen Bowen is out with a hurt left knee. Starting tight end Jordan Reed is out with a concussion, so Fred Davis is active for the first time since Washington's fifth game.
AP NFL website: www.pro32.ap.org