Warren was 20 of 29 from the field, including 9 of 12 from beyond the 3-point arc. Warren's previous career high was 40.
Aaron Holiday had 15 points and 10 assists, and Victor Oladipo added 15 points for the Pacers, who improved to 40-26 despite playing without key injured players such as Domantas Sabonis and Malcolm Brogdon.
Joel Embiid was spectacular for the Sixers (39-27) with 41 points, 21 rebounds, four assists and three blocked shots. It was his fourth game this season with at least 30 points and 15 rebounds. Tobias Harris scored 30 points, and Ben Simmons added 19 points and 13 rebounds.
Kyle Lowry had 33 points, 14 rebounds and six assists, leading Toronto past Los Angeles for the for the 11th consecutive time.
Lowry hit 5 of 9 3-pointers and 8 of 16 shots from the floor. OG Anunoby had 23 points, making 8 of 9 shots, and Pascal Siakam contributed 15 points and nine rebounds for the Raptors. The Raptors haven't lost to the Lakers since Nov. 30, 2014.
Bam Adebayo had 22 points, nine rebounds and six assists, Jimmy Butler also scored 22 points and added seven assists, and Miami used a big second half to beat Denver.
Kelly Olynyk scored all 20 of his points in the fourth quarter, Duncan Robinson scored 17, Goran Dragic had 13 points and Kendrick Nunn added 11 for the Heat (42-24). Miami outscored Denver 69-48 in the second half.
Nikola Jokic had 19 points, seven rebounds and six assists, and Jerami Grant also had 19 points for the short-handed Nuggets (43-23). Denver played without starters Jamal Murray, Gary Harris and Will Barton.
Paul George scored 28 points and led a 3-point barrage as Los Angeles routed New Orleans.
The Clippers (45-21) tied a franchise record for 3-pointers made in a half when they hit 16 of 24 on their way to a 77-45 halftime lead. They were one 3-pointer shy of the NBA record for a first half. They finished 25 of 47, falling short of the Golden State Warriors' NBA record 27 3-pointers in a game.
The 32-point halftime deficit was the largest in franchise history for the Pelicans (28-38), who saw their playoff hopes continue to fade.
Shai Gilgeous-Alexander scored 19 points as Oklahoma City took control early to beat Utah in their first game of the NBA's restart.
Utah (42-24) was led by Donovan Mitchell's 13 points, though Mitchell was just 5 of 15 from the floor.
--Field Level Media