| | P | Return of 27th man (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | P | Called Up from Minors (Signed) |
| | P | Released (Signed) |
| | CF | Transferred to 60-Day IL (Strained left quad) |
| | 3B | Purchased From Minors (Signed) |
| | SS | Sent to Minors (Signed) |
| | 2B | Purchased From Minors (Signed) |
| | C | Called Up from Minors (Signed) |
| | P | Transferred to 60-Day IL (Strained left knee) |
| | P | Sent to Minors (Signed) |
| | LF | Sent to Minors (Signed) |
| | 2B | Traded (for 2B Whit Merrifield, 3-player deal) From |
| | P | Traded (for 2B/OF Whit Merrifield, 3-player deal) From |
| | LF | Traded (for C Cam Gallagher) From |
| | 2B | Traded (for INF Samad Taylor & RHP Max Castillo) To |
| | C | Traded (for OF Brent Rooker) To |
| | P | Sent to Minors (Signed) |
| | P | Traded (for 3B Emmanuel Rivera) From |
| | P | Recalled From Minors Rehab (Signed) |
| | 3B | Traded (for RHP Luke Weaver) To |
| | P | Sent to Minors (Signed) |
| | 3B | NTR - Called Up From Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Traded (for cash considerations) From |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors (Signed) |
| | C | Removed From 10-Day IL (Torn ligament, left hand) |
| | C | Recalled From Minors Rehab (Signed) |
| | 3B | Sent to Minors (Signed) |
| | SS | Called Up from Minors (Signed) |
| | P | Traded (for OF Andrew Benintendi, 4-player deal) From |
| | LF | Traded (for LHP T.J. Sikkema, four-player deal) To |
| | P | Called Up from Minors (Signed) |
| | C | Sent to Minors for Rehabilitation (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | CF | Placed on 10-Day IL (Strained left quad) |
| | 1B | Called Up from Minors (Signed) |
| | C | Reinstated From Restricted List (Signed) |
| | RF | Reinstated From Restricted List (Signed) |
| | P | Reinstated From Restricted List (Signed) |
| | P | Reinstated From Restricted List (Signed) |
| | CF | Reinstated From Restricted List (Signed) |
| | CF | Released (Signed) |
| | P | Reinstated From Restricted List (Signed) |
| | P | Released (Signed) |
| | 3B | Reinstated From Restricted List (Signed) |
| | C | Reinstated From Restricted List (Signed) |
| | LF | Reinstated From Restricted List (Signed) |
| | 1B | Sent to Minors (Signed) |
| | C | Sent to Minors (Signed) |
| | SS | Sent to Minors (Signed) |
| | 2B | Outrighted to Minors (return of Replacement Player) |
| | LF | Outrighted to Minors (return of Replacement Player) |
| | C | Outrighted to Minors (return of Replacement Player) |
| | 3B | Outrighted to Minors (return of Replacement Player) |
| | P | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | 2B | Reinstated From Restricted List (Signed) |
| | P | Traded (for RHP Jonatan Bernal) To |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (return of Replacement Player) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (recalled as Replacement Player) |
| | C | Called Up from Minors (Signed) |
| | SS | Called Up from Minors (Signed) |
| | 1B | Called Up from Minors (Signed) |
| | CF | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | P | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | 2B | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | C | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | 2B | Purchased From Minors (selected as Replacement Player) |
| | P | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | 3B | Purchased From Minors (selected as Replacement Player) |
| | RF | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | C | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | C | Purchased From Minors (selected as Replacement Player) |
| | 3B | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | P | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | LF | Called Up from Minors (selected as Replacement Player) |
| | LF | Placed on Restricted List (COVID-19 protocol travel restrictions) |
| | P | Return of 27th man (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | CF | Sent to Minors (Signed) |
| | P | Designated for Assignment (Signed) |
| | CF | Traded (three-player deal for 2022 CB Pick #35) From |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Acquired Off Waivers (Signed) To |
| | P | Outrighted to Minors (Signed) |
| | P | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Outrighted to Minors (return of Replacement Player) |
| | P | Sent to Minors (Signed) |
| | P | Acquired Off Waivers (Signed) From |
| | P | Designated for Assignment (Signed) |
| | P | Called Up from Minors (Signed) |
| | 1B | Traded (for RHP Wyatt Mills, three-player deal) To |
| | P | Sent to Minors (Signed) |
| | P | Traded (for 1B Carlos Santana, three-player deal) From |
| | P | Designated for Assignment (Signed) |
| | 1B | Purchased From Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | C | Placed on 10-Day IL (Torn ligament, left hand) |
| | CF | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | CF | Removed From 10-Day IL (Right quad strain) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Acquired Off Waivers (Signed) To |
| | C | Removed From 10-Day IL (Strained left hamstring) |
| | C | Recalled From Minors Rehab (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Designated for Assignment (Signed) |
| | P | Outrighted to Minors (Signed) |
| | 2B | Signed (loses arbitration) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | CF | Released (Signed) |
| | P | Purchased From Minors (selected as Replacement Player) |
| | P | Placed on 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | P | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Sent to Minors (Signed) |
| | P | Recalled From Minors Rehab (Signed) |
| | P | Transferred to 60-Day IL (Left elbow surgery - out for season) |
| | CF | Sent to Minors for Rehabilitation (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Signed to a Minor League Contract (Signed) |
| | P | Sent to Minors for Rehabilitation (Signed) |
| | CF | Outrighted to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Designated for Assignment (Signed) |
| | CF | Removed From 10-Day IL (COVID-19 injured list (positive test)) |
| | CF | Recalled From Minors Rehab (Signed) |
| | P | Traded (for RHP Yohanse Morel) From |
| | CF | Sent to Minors for Rehabilitation (Signed) |
| | C | Sent to Minors for Rehabilitation (Signed) |
| | P | Placed on 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Placed on 10-Day IL (COVID-19 injured list (positive test)) |
| | LF | Outrighted to Minors (return of Replacement Player) |
| | P | Called Up from Minors (Signed) |
| | P | Purchased From Minors (Signed) |
| | P | Purchased From Minors (Signed) |
| | RF | Removed From 10-Day IL (COVID-19 injured list) |
| | C | Removed From 10-Day IL (Sprained left thumb) |
| | C | Sent to Minors (Signed) |
| | LF | Purchased From Minors (selected as Replacement Player) |
| | RF | Placed on 10-Day IL (COVID-19 injured list) |
| | P | Placed on 10-Day IL (COVID-19 injured list (positive test)) |
| | P | Called Up from Minors (recalled as Replacement Player) |
| | C | Signed to a Minor League Contract (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Removed From 10-Day IL (COVID-19 injured list) |
| | P | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | SS | Transferred to 60-Day IL (Torn ACL, left knee) |
| | P | Placed on 10-Day IL (COVID-19 injured list) |
| | P | Called Up from Minors (Signed) |
| | P | Purchased From Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Purchased From Minors (Signed) |
| | CF | Placed on 10-Day IL (COVID-19 injured list (positive test)) |
| | C | Placed on 10-Day IL (Sprained left thumb) |
| | C | Called Up from Minors (Signed) |
| | P | Return of 27th man (Signed) |
| | P | Called Up from Minors (recalled as 27th roster player) |
| | LF | Signed (wins arbitration) |
| | 1B | Removed From 10-Day IL (Right ankle bursitis) |
| | C | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | CF | Placed on 10-Day IL (Right quad strain) |
| | C | Called Up from Minors (Signed) |
| | C | Return of 27th man (Signed) |
| | C | Called Up from Minors (recalled as 27th roster player) |
| | 1B | Placed on 10-Day IL (Right ankle bursitis) |
| | 3B | Called Up from Minors (Signed) |
| | C | Called Up from Minors (Signed) |
| | C | Placed on 10-Day IL (Strained left hamstring) |
| | P | Sent to Minors (Signed) |
| | 3B | Sent to Minors (Signed) |
| | P | Called Up from Minors (Signed) |
| | P | Placed on 10-Day IL (Left elbow surgery - out for season) |
| | P | Acquired Off Waivers (Signed) To |
| | P | Sent to Minors (Signed) |
| | 3B | Called Up from Minors (Signed) |
| | RF | Called Up from Minors (Signed) |
| | SS | Placed on 10-Day IL (Torn ACL, left knee) |
| | P | Designated for Assignment (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Traded (for cash considerations) From |
| | P | Called Up from Minors (Signed) |
| | RF | Sent to Minors (Signed) |
| | P | Cleared Waivers and Became a Free Agent (Signed) |
| | P | Released (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Reinstated from Bereavement/Family Medical Emergency List (Signed) |
| | P | Designated for Assignment (Signed) |
| | P | Placed on Bereavement/Family Medical Emergency List (Signed) |
| | SS | Purchased From Minors (Signed) |
| | 3B | Sent to Minors (Signed) |
| | 2B | Signed (restructured one-year contract extension) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | C | Sent to Minors (Signed) |
| | C | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | SS | Sent to Minors (Signed) |
| | 1B | Sent to Minors (Signed) |
| | C | Signed (avoids arbitration) |
| | 1B | Signed (one-year contract) |
| | P | Signed (avoids arbitration) |
| | P | Signed (avoids arbitration) |
| | P | Signed (avoids arbitration) |
| | SS | Signed (avoids arbitration) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Sent to Minors (Signed) |
| | P | Traded (with cash for LHP Amir Garrett) To |
| | P | Traded (for LHP Mike Minor and cash) From |
| | P | Signed as Free Agent (one-year contract) |
| | P | Signed to a Minor League Contract (Signed) |
| | P | Signed to a Minor League Contract (Signed) |
| | P | Signed to a Minor League Contract (Signed) |
| | P | Signed to a Minor League Contract (Signed) |
| | P | Signed to a Minor League Contract (Signed) |
| | 2B | Signed to a Minor League Contract (Signed) |
| | P | Signed to a Minor League Contract (Signed) |
| | CF | Signed to a Minor League Contract (Signed) |
| | P | Signed as Free Agent (one-year contract) |
| | P | Free Agent - No Contract Offer (non-tendered) |
| | P | Cleared Waivers and Became a Free Agent (Signed) |
| | P | Retired (Signed) |
| | P | Released (Signed) |
| | C | Purchased From Minors (Signed) |
| | P | Purchased From Minors (Signed) |
| | P | Purchased From Minors (Signed) |
| | P | Purchased From Minors (Signed) |
| | SS | Acquired Off Waivers (Signed) To |
| | P | Designated for Assignment (Signed) |
| | 1B | Purchased From Minors (Signed) |
| | SS | Purchased From Minors (Signed) |
| | CF | Declared Free Agency (Signed) |
| | C | Refused Minor League Assignment - Free Agent (Signed) |
| | P | Refused Minor League Assignment - Free Agent (Signed) |
| | P | Declared Free Agency (Signed) |
| | P | Declared Free Agency (Signed) |
| | SS | Declared Free Agency (Signed) |
| | SP | Declared Free Agency (Signed) |
| | SS | Declared Free Agency (Signed) |
| | CF | Declared Free Agency (Signed) |
| | 1B | Signed to Play in Japan (Hiroshima Carp) |
| | P | Refused Minor League Assignment - Free Agent (Signed) |
| | P | Outrighted to Minors (Signed) |