Career Leaders

    Losses

PlayerLosses
Cy Young316
Pud Galvin305
Nolan Ryan292
Walter Johnson279
Phil Niekro274
Gaylord Perry265
Jack Powell256
Don Sutton256
Eppa Rixey251
Bert Blyleven250
Warren Spahn245
Robin Roberts245
Early Wynn244
Steve Carlton244
Jim Kaat237
Frank Tanana236
Gus Weyhing234
Tommy John231
Ted Lyons230
Bob Friend230
Greg Maddux227
Tim Keefe226
Fergie Jenkins226
Red Ruffing225
Bobo Newsom222
Jack Quinn218
Sad Sam Jones217
Charlie Hough216
Chick Fraser216
Jim McCormick214
Tony Mullane214
Mickey Welch214
Red Faber213
Paul Derringer212
Burleigh Grimes212
Jamie Moyer209
Jerry Koosman209
Vic Willis208
Pete Alexander208
Kid Nichols205
Tom Seaver205
Joe Niekro204
Jim Whitney204
Tom Glavine203
Adonis Terry202
George Mullin196
Old Hoss Radbourn196
Claude Osteen195
Eddie Plank194
Dennis Martinez193
Jerry Reuss191
Tom Zachary191
Rick Reuschel191
Mickey Lolich191
Christy Mathewson188
Mike Morgan186
Mel Harder186
Jack Morris186
Earl Whitehill185
Jim Bunning184
Roger Clemens184
Al Orth184
Joe Bush183
Larry Jackson183
Curt Simmons183
Danny Darwin182
Waite Hoyt182
Hooks Dauss182
Murry Dickson181
Dutch Leonard181

Bartolo Colon*

181
Rick Wise181
Tim Wakefield180
Lee Meadows180
Dolf Luque179
Wilbur Cooper178
Livan Hernandez177
John Clarkson177
Rube Marquard177
Mike Moore176
Bill Dineen176
Long Tom Hughes175
Pink Hawley175
Jim Perry174
Doyle Alexander174
Bob Gibson174
Chuck Finley173
Luis Tiant172
Red Donahue172
Red Ehret171
Larry French171
Dennis Eckersley171
Camilo Pascual170
Bert Cunningham170
Billy Pierce169
Amos Rusie167
Red Ames167
Jim Clancy167
George Uhle166
Ted Breitenstein166