The bigger loss for the Tigers, was Miguel Cabrera. The veteran first baseman left the game in the third inning with ruptured left biceps tendon, and he will undergo season-ending surgery.
Cabrera sustained the injury on a swing and miss at a Jake Odorizzi breaking pitch.
Adrianza's seventh-inning homer, his third of the season, gave the Twins a three-run lead. Adrianza had three hits and scored twice.
Yankees 3, Nationals 0
Didi Gregorius homered twice, leading New York past visiting Washington.
Gregorius recorded his fourth career multi-homer game and third this season. He set a team record for multi-homer games by a shortstop in a single season and homered for the first time since May 23.
CC Sabathia (4-1) allowed four hits in 5 2/3 innings and became the fifth pitcher to get 1,500 strikeouts for the Yankees. He joined Andy Pettitte, Ron Guidry, Whitey Ford and Red Ruffing.
Phillies 5, Rockies 4
Aaron Nola pitched 6 2/3 strong innings, and Scott Kingery homered and knocked in four runs to lead Philadelphia past visiting Colorado.
Nola (8-2) allowed just one run on four hits and no walks. He struck out 10. Philadelphia led 5-1 through eight innings, but Colorado scored three times in the ninth before leaving the potential tying and go-ahead runs on base.
Rockies starter Jon Gray (6-7) gave up four runs on just three hits in six innings. He walked four and fanned 10.
Brewers 4, Cubs 0
Chase Anderson, Taylor Williams and Jacob Barnes combined to pitch a two-hit shutout as host Milwaukee cruised to a win over Chicago.
Travis Shaw finished 2-for-3 with two doubles and a season-high four RBIs to lead the Brewers at the plate. Anderson (5-5) allowed one hit and two walks while striking out six in seven innings.
Willson Contreras and Addison Russell tallied the only hits for Chicago, which was blanked for the fifth time this year. The Cubs lost to the Brewers for only the second time in 10 meetings this season.
Rays 4, Blue Jays 1
Wilson Ramos hit a two-run homer to open the scoring, and Tampa Bay went on to defeat Toronto in St. Petersburg, Fla. The Rays have won the first two games of the three-game series.
Ryne Stanek started on the mound for the Rays, pitching two perfect innings with three strikeouts. He was replaced by Austin Pruitt (2-3), who allowed one run and four hits with one strikeout in 2 2/3 innings.
Sergio Romo pitched around a single in the ninth inning to earn his second save of the season.
Marlins 3, Giants 1
Trevor Richards earned his first major league victory, leading Miami past visiting San Francisco Giants.
Making his seventh major league start, Richards (1-3) overcame a wild start but allowed just two hits, three walks and one run in six innings. He struck out two. The Marlins got three scoreless innings of relief, one each from Adam Conley, Brad Ziegler and Kyle Barraclough, who earned his fourth save.
Miami's offensive stars were JT Riddle, who hit a go-ahead, two-run double; and Starlin Castro, who went 2-for-4 with one RBI. Riddle also made a stellar defensive play.
Red Sox 6, Orioles 4
Rafael Devers and Andrew Benintendi both homered as Boston won at Baltimore.
Eduardo Rodriguez (8-1) won his career-best fifth consecutive start. He allowed two runs on eight hits in 5 2/3 innings.
The Orioles lost their six game in a row and fell for the 13th time in 15 games.
Reds 5, Royals 1 (10 innings)
Joey Votto delivered a tiebreaking, three-run triple in the top of the 10th inning to lead Cincinnati to a victory at Kansas City.
Tucker Barnhart hit a tying homer in the ninth to keep the Reds from being blanked. The win was just Cincinnati's third in the past nine games.
Hunter Dozier homered and Ian Kennedy threw eight shutout innings for the Royals, who lost for the eighth time in their past nine games.
Padres 4, Cardinals 2
Relievers Matt Strahm and Adam Cimber retired the first 15 Cardinals they faced in a "bullpen start," and Eric Hosmer homered to start a three-run, fourth-inning rally, leading San Diego to a win at St. Louis.
The Cardinals didn't have a baserunner until Harrison Bader led off the sixth with an infield single. St. Louis then scored two runs in the bottom of the seventh against Craig Stammen.
Strahm retired all nine hitters he faced with four strikeouts. Cimber (3-2) worked the next three scoreless innings, allowing only Bader's hit with three strikeouts to get credit for the win. Brad Hand recorded his 20th save.
White Sox 5, Indians 1
James Shields earned his first win since Opening Day, and Yoan Moncada and Yolmer Sanchez hit back-to-back homers to start the first inning as Chicago beat visiting Cleveland.
The White Sox have alternated wins with losses over the past seven games. The Indians lost for the second time in seven games.
Shields (2-7) allowed one run on four hits and no walks while striking out two over seven innings. He was 0-7 with a 4.83 ERA in 13 games (12 starts) since earned the win against the Kansas City Royals on Opening Day.
Braves 8, Mets 2
Ozzie Albies blasted a grand slam to cap a six-run outburst in the sixth inning and lead host Atlanta to a win over New York.
It was the second grand slam in the past month for Albies, and his 16th homer of the season. The second baseman leads the National League with 37 extra-base hits and 53 runs.
Braves starter Mike Foltynewicz threw five scoreless innings and allowed only two hits. Reliever Shane Carle (4-1) pitched two-thirds of an inning and was the beneficiary of the go-ahead rally.
Diamondbacks 13, Pirates 8
Jon Jay had three hits, including three-run homer, and Ketel Marte had two hits and drove in three runs as Arizona took an 8-0 lead and held on for a victory over Pittsburgh in Phoenix.
Paul Goldschmidt, Marte and John Ryan Murphy collected two hits apiece for the Diamondbacks, who have scored 51 runs during a five-game winning streak. Jay, acquired Thursday from the Royals, was 0-for-12 in his first four games with the Diamondbacks before Tuesday.
Starling Marte hit a three-run homer, and Josh Bell and Josh Harrison had three hits and an RBI apiece for the Pirates.
Dodgers 12, Rangers 5
Max Muncy homered in a fourth consecutive game, and Yasiel Puig drove in three runs as Los Angeles rolled to a victory over visiting Texas.
The Dodgers have won 18 of their past 24 games. By winning the opener of a two-game interleague matchup, they have assured themselves of going unbeaten in their past eight series.
The Rangers fell to a season-high 15 games under .500 while losing their fifth consecutive game. They have dropped eight of their past 11.
Mariners 6, Angels 3
Mitch Haniger and Ryon Healy each homered twice to match Mike Trout, who accomplished the feat for the second consecutive game, as host Seattle defeated Los Angeles.
Mike Leake pitched six innings of one-run ball for the Mariners, who have won 10 of their past 12 games.
Edwin Diaz worked a 1-2-3 ninth, striking out Trout to end the game and post his major-league-leading 25th save of the season. Trout leads the majors with 23 homers.
Astros 6, A's 3
Evan Gattis drove in a career-high five runs with a three-run home run and a two-run double, propelling Houston to a victory at Oakland.
Lance McCullers Jr. (8-3) went seven innings, allowing two runs and five hits. He walked three and struck out five, beating the A's for the third time this season.
Brad Peacock struck out Stephen Piscotty with the potential tying runs aboard to end the eighth inning, protecting a lead that turned into the Astros' sixth straight win. Ken Giles pitched the ninth inning for his 11th save.
--Field Level Media