The Latest: Browns without starting tackles vs. Cardinals

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The Latest on Week 6 in the NFL (all times EDT):

2:40 p.m.

Browns quarterback Baker Mayfield’s flanks will be protected by backups against the Arizona Cardinals.

Cleveland is without starting right tackle Jack Conklin as well as starting left tackle Jedrick Wills Jr. Conklin hurt his right knee in last week’s loss to the Chargers while Wills has been dealing with an ankle injury since Week 1.

Blake Hance will make his second straight start for Wills while rookie James Hudson will fill in for Conklin.

The Browns will also be without star running back Nick Chubb, who is sidelined with a calf injury.

It helps the Browns that Arizona is missing star edge rusher Chandler Jones, who tested for positive for COVID-19 earlier this week and is out.

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2:15 p.m.

Indianapolis Colts receiver Parris Campbell has been ruled out after injuring his foot against Houston.

Campbell's injury came after he caught a 51-yard TD pass from Carson Wentz for Indy’s first score and his first touchdown since Sept. 15, 2019.

The Colts did get a boost with a return to the lineup for receiver T.Y. Hilton. Hilton has three catches for 70 yards after missing the first five games with a neck injury.

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2 p.m.

The Baltimore Ravens are finding plenty of running room so far against the Chargers.

Passing room, too.

Le’Veon Bell scored on a 2-yard run early in the second quarter to give Baltimore a 14-0 lead over Los Angeles in this matchup of first-place teams. The Ravens have scored on their first two possessions, and they already have 92 yards rushing — a week after their 43-game streak of reaching 100 yards on the ground was snapped.

Baltimore has only faced one third down so far. Lamar Jackson is 8 of 9 for 77 yards.

The Ravens do have an injury to deal with on defense. Linebacker Patrick Queen left in the first quarter with a thigh problem.

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1:50 p.m.

Patrick Mahomes has thrown an interception for the fifth consecutive game.

The Kansas City Chiefs quarterback’s pass went through Tyreek Hill’s hands and was picked off by Washington cornerback Kendall Fuller in the second quarter Sunday. The turnover gave Washington the ball at its own 6.

Mahomes, the NFL MVP in 2018, now has been intercepted a total of seven times already this season in less than 5 1/2 games so far. That surpasses his final totals of six picks last season and five the season before that.

The five-game streak with at least one interception matches one in 2018 for the longest of his career. The last Chiefs quarterback with a longer one was Matt Cassel, who did it in eight straight games in 2012.

The Chiefs came into Sunday with a minus-7 turnover differential for the season, ahead of only Jacksonville in the entire NFL.

Mahomes was picked off twice in last week’s loss to Buffalo.

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1:25 p.m.

Already missing coach Kliff Kingsbury and star linebacker Chandler Jones due to positive COVID-19 tests, unbeaten Arizona placed defensive lineman Corey Peters on the reserve/COVID-19 list hours before playing the Browns in Cleveland.

Kingsbury was ruled out Friday along with quarterbacks coach Cam Turner and defensive tackle Zach Allen.

Jones, one of the league’s best edge rushers, was placed on the list COVID-19 list on Tuesday.

The loss of Peters weakens Arizona’s depth up front.

Defensive coordinator Vance Joseph and special teams coordinator Jeff Rodgers are splitting Kingsbury’s duties as the Cardinals try to continue their best start since 1974.

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1:20 p.m.

The New York Giants have lost rookie wide receiver Kadarius Toney on the first series against the Los Angeles Rams.

The elusive first-round draft pick aggravated an ankle injury. He had three catches for 36 yards in helping to set up a field goal. Toney set a rookie record for the Giants last week with 10 catches for 189 yards.

New York came into the game short at the wide receiver spot with Kenny Golladay out with a knee injury and Darius Slayton out for the third straight week with a hamstring injury

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12:55 p.m.

The Jacksonville Jaguars have ended their 20-game skid.

Matthew Wright has just made a 53-yard field goal on the final play of the Jaguars game in London against the Miami Dolphins to give Jacksonville a 23-20 win that snapped the NFL's second longest losing streak ever.

Only the expansion Tampa Bay Buccaneers lost more consecutive games with 26 to start their franchise in 1976-77.

Wright had tied the game earlier in the fourth quarter with a 54-yard field goal and also hit a 40-yarder in the first quarter.

The Jaguars came into the game as the only team in the Super Bowl era without a made field goal in the first games five games of a season.

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12:30 p.m.

The Panthers are once again playing without star running back Christian McCaffrey, who was placed on injured reserve on Saturday with a strained hamstring.

McCaffrey, who has already missed two games this season due to the hamstring, will miss at least the next three games. He is eligible to return Nov. 7 against the New England Patriots.

That means McCaffrey will have missed 18 of 24 games since signing a four-year, $64 million deal that made him the league’s highest paid running back.

Running back Dalvin Cook is active for the Vikings for the game against Carolina.

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2:15 p.m.

Tua Tagovailoa has thrown his second TD pass of the day to former college teammate Jaylen Waddle to give the Miami Dolphins a 20-17 lead early in the fourth quarter over the Jacksonville Jaguars.

Tagovailoa is making his first start in a month, returning from fractured ribs. He connected with Waddle on a 6-yard TD pass on the opening drive and a 2-yarder earlier in the fourth as the former Alabama stars have found a rhythm.

The go-ahead score came after the Jaguars were stopped on a fourth-and-1 from the Miami 9 when coach Urban Meyer bypassed a short field goal.

The winless Jags (0-5) have lost 20 consecutive games. The Dolphins (1-4) have dropped four straight headed into the NFL's second game this season in London.

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9:15 a.m.

Tua Tagovailoa and Trevor Lawrence square off in London as the Miami Dolphins and Jacksonville Jaguars both try to halt losing streaks.

The winless Jags (0-5) have lost 20 consecutive games. The Dolphins (1-4) have dropped four straight.

Tagovailoa is making his first start in a month, returning from fractured ribs.

It's the second and final NFL game in London this season. Tottenham Hotspur Stadium is the setting.

The temperature was 60 degrees Fahrenheit and no rain expected ahead of the 2:30 p.m. kickoff local time.

It's a home-away-from-home game for the Jags but there are fans of all stripes, wearing a variety of team jerseys.

One cheesehead was spotted wearing an Aaron Rodgers jersey.

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