The Browns ended up scoring an opening touchdown anyway.
Mayfield completed his next four passes for 54 yards, including a 17-yard strike in the end zone to Jarvis Landry. Landry, though, drew a taunting penalty after the score.
The Bills chose to enforce the 15-yard penalty on the PAT, and Austin Seibert‘s kick was wide right. The Browns lead 6-0.
Landry caught three passes for 47 yards and the touchdown on the drive.
The Bills ended their first possession on downs, failing on a fourth-and-four play from the Browns 39 as Josh Allen threw an errant pass.