The 2021 All-Star Futures Game included New York's Nos. 1 and 5 overall prospects, who each entered midway through the seven-inning showcase.
Dominguez made a pinch-hit appearance in the third inning, ripping a line drive to his left but going directly at 3B Nolan Gorman.
Dominguez, 18, went 0 for 3 with a pair ofstrikeouts swinging in the fifth and seventh innings. The American League Futures lost 8-3 to the National League Futures.
He allowed two hits but stranded both runners at second and third, striking out two while walking one on 28 pitches (17 strikes).