The 49ers announced Friday morning that Jimmy Garoppolo (ankle) would be out for Sunday's game against the Giants, meaning Nick Mullens would be the starting quarterback for San Francisco come kickoff time at MetLife Stadium.
The Giants already had a big opportunity to "steal" a win from the reigning NFC Champions this week after the 49ers lost Nick Bosa and Solomon Thomas for the season to torn ACL's, but now that both sides of the ball seem compromised, the Giants have a real shot at getting their first win of the season.
New York brought in veteran RB Devonta Freeman this week to join Dion Lewis and Wayne Gallman out of the backfield, and Daniel Jones still has a number of guys to throw to in Golden Tate, Darius Slayton and Evan Engram.
This game was definitely one of those on the Giants schedule that most people tossed up as a likely loss, but now Big Blue has a legitimate shot at getting their first win and putting their season back on track.
But Joe Judge also doesn't want the Giants to get ahead of themselves, because even with backups coming in, these are still professionals.
"Nick's a good quarterback, he's a competitive dude, he's a tough dude," Judge said about Mullens. "He's comfortable in the pocket, gets the ball out of his hands really quick, he's an accurate passer. ...We expect this guy to fight and give his team every advantage possible."