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Portugal centre-back Jose Fonte's late header rescued Ligue 1 leaders Lille a 1-1 draw against Strasbourg on Sunday which kept them two points ahead of the chasing pack as Lyon were held by Marseille, while Monaco moved closer to the top of the table by cruising past Brest.
Lille extended their lead over second-placed Paris Saint-Germain and stayed three points clear of Lyon, who missed the chance to move within a point after a 1-1 draw at Marseille.
Monaco sit in fourth place, only four points off the summit.
Christophe Galtier's Lille, bidding for a first major trophy since winning the league and French Cup double in 2011, are unbeaten in nine league games since a defeat by Angers in early January, but lost both legs of their Europa League last-32 tie.
"We're disappointed," Fonte told Canal+. "We did everything in the second half, but we have to create more chances.
"But we didn't lose... There was perhaps a bit of fatigue from the game (on Thursday) against Ajax, but there are no excuses, we have to do better.
"It's a disappointment, but we continue the fight. It's not over."
Home team Lille started on the front foot and had a penalty appeal waved away in the 17th minute after Jonathan David went down in the area, despite a VAR review.
But they fell behind nine minutes before half-time as Strasbourg striker Ludovic Ajorque volleyed home.
Ajorque almost doubled his tally two minutes later, but his header was well saved by Lille goalkeeper Mike Maignan.
Sven Botman saw a header kept out by Strasbourg's Eiji Kawashima and David also fired over before the break.
Two good second-half chances both fell to Jonathan Ikone, but the young Lille forward, who snapped a 10-game goal drought in the win over Lorient last weekend, saw his low effort saved by Kawashima and a header fly over.
But Lille were not to be denied the point which ensured they would end the weekend top, as Fonte rose highest to head home Benjamin Andre's cross with four minutes remaining.
- Lyon undone by controversial penalty -
Lyon were quick out of the blocks and looked to be on their way to a seventh win in eight games when Karl Toko Ekambi collected Lucas Paqueta's pass and netted his 12th goal of the campaign.
Paqueta remained in the centre of the action, as the Brazil midfielder conceded a penalty for handball shortly before the interval, despite the ball appearing to strike his body before rebounding onto his arm.
Arkadiusz Milik dispatched the spot-kick to claim his second goal for Marseille since joining on loan from Napoli in January.
The only incident of note in a cagey second half was when Paqueta was given a second yellow card for bringing down Dimitri Payet, having also been booked in the controversial penalty decision.
But seventh-placed Marseille never looked like finding a winner.
Earlier on Sunday, Monaco extended their unbeaten run to 12 games with a 2-0 win over Brest.
Goals deep into the second half from Stevan Jovetic and Kevin Volland sealed the Principality club's ninth win from their last 10 outings.
At Monaco's Stade Louis II, Brest goalkeeper Gautier Larsonneur had kept the visitors in the hunt, especially when denying Wissam Ben Yedder from the penalty spot after half an hour.
But he was finally beaten by Jovetic in the 75th minute, with German forward Volland cementing the three points in the final minute.
Monaco are now 14 points clear of fifth-placed Metz, but coach Niko Kovac is still focused on securing fourth, which provides a Europa League spot.
"The top three? Yes, it's taboo," he said. "When we have enough points to ensure the fourth place, we'll talk about it (top three)."
PSG bounced back from their 2-0 loss to Monaco at the Parc des Princes with a Kylian Mbappe-inspired 4-0 victory over last-placed Dijon on Saturday.