Price (4-2, 3.39 ERA) threw just 73 pitches his last time out against the Minnesota Twins, allowing one run on four hits in five innings. After the game, Red Sox manager Alex Cora said the quick hook was designed to help "take care" of the 33-year-old, though he noted the move was not injury related.
"It was a collective decision," said Price, who spent time on the injured list earlier this season with left elbow tendinitis. "That wasn't on Alex. It wasn't on him. I'm feeling all right."
Price has reached 100 pitches just once in his last nine starts, in a win against the Tampa Bay Rays on June 8. He threw 97 in a no-decision against the White Sox on May 2, giving up three runs on seven hits in six innings.
For his career, Price is 6-5 with a 3.45 ERA in 16 starts against the White Sox.
Opposing Price will be fellow Vanderbilt alum Carson Fulmer (1-1, 6.35). The right-hander will get the nod as part of a bullpen day for Chicago.
Fulmer, like Price a former first-round draft pick, will make his first major league start since May 2018. He has reached three innings out of the bullpen in just two of his nine appearances this season.
Fulmer has faced the Red Sox twice in relief in his career, allowing five runs (three earned) in one total inning.
Boston rallied three times in winning the first game of the series Monday night. The Red Sox tied the score at 2-2, 3-3 and 5-5 before ultimately proving victorious when Marco Hernandez beat out an infield single with the bases loaded in the ninth inning.
"We were pleased we were scoring, but we let some chances slip away," Cora said. "There was a lot of stuff that didn't go right, but in the end, we won. That's the most important thing."
For Cora's squad on offense, Mookie Betts was among the bright spots with just his second home run in his last 11 games. For Chicago, former Red Sox Yoan Moncada had two hits, including his first homer of the season from the right side of the plate.
White Sox shortstop Tim Anderson went 0-for-5 with four strikeouts as his nine-game hitting streak ended.
"I think the story today was we really did put ourselves in a good position to win a ballgame," White Sox manager Rick Renteria said. "Both clubs ended up battling. Even though we had some shining moments, we ended up a little short."
With the win, the Red Sox avoided a three-game losing streak while sending the White Sox to their third straight defeat. Chicago has dropped six of its last eight games.
Prior to Tuesday's game, Boston is expected to activate knuckleball reliever Steven Wright for the first time this season. Wright was suspended the first 80 games after testing positive for a performance-enhancing substance during spring training.
--Field Level Media