It is unclear how or when Fluellen got hurt.
He has not practiced since before the Titans’ preseason opener Aug. 8.
Fluellen, 27, ended last season on injured reserve after injuring his knee against the Patriots on Nov. 11. He played seven games.
Fluellen has eight carries for 37 yards in his career and 11 special teams tackles.
He joined the Titans in 2015 as an undrafted free agent. Flulellen has played 23 games for the Titans the past two seasons.