Chiefs 2022 schedule with game-by-game score predictions

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The regular-season schedule for the 2022 NFL season has been revealed.

We now know exactly when the Kansas City Chiefs will play their opponents during the upcoming season and it’s quite the grueling schedule. With that in mind, here are some quick-hitting way-too-early game-by-game score predictions for you to consider.

Take a look at some thoughts on the Chiefs’ schedule, the games we think they’ll win, plus those we think they could lose down below:

Week 1: Chiefs at Cardinals

Michael Chow-Arizona Republic

This feels like a great time to catch the Cardinals. Kyler Murray and the organization have seen some drama between them this offseason. Their star receiver, Deandre Hopkins, will be serving a suspension. There is going to be no tape on this new offense from Andy Reid and the Chiefs save for the preseason. A solid game plan could catch this Arizona team with their pants down so to speak. Begin the season with a win in Arizona, end the postseason with a win in Arizona.

Prediction: Chiefs win 35-13

Week 2: Chiefs vs. Chargers (TNF)

AP Photo/Ed Zurga

Realistically, the Chiefs had a lot of turnover in their offensive skill positions this offseason and a lot of turnover in the defensive secondary too. Looking at this matchup, I’m wondering whether we’re going to see the newness of the roster in Kansas City come into play on a short week early in the season. At the same time, I think teams are going to have a tougher time figuring the Chiefs’ offense out without Tyreek Hill on the field.

Prediction: Chiefs win 27-24.

Week 3: Chiefs at Colts

Mark J. Rebilas-USA TODAY Sports

The Colts haven’t been able to get the quarterback position right since Andrew Luck retired. I think Matt Ryan is capable of being a good bridge option for the team, but in a loaded AFC conference can he compete with the best-of-the-best? Gus Bradley has better personnel with the Colts than he did with the Raiders, but the Chiefs outscored his defenses 89-21 last year.

Prediction: Chiefs win 33-20

Week 4: Chiefs at Buccaneers (SNF)

AP Photo/Charlie Riedel

This will be the first time these two teams have played since Super Bowl LV. It’ll also likely be the last time that Patrick Mahomes and Tom Brady play each other. With a 3-2 all-time record between them, I’d like to think that the legacy implications of Mahomes tying up the series is something that would motivate Kansas City to come out on top. At the same time, with three weeks of film of the Chiefs’ new-look offense, I think that Bucs HC Todd Bowles will put up a good fight.

Prediction: Chiefs win 28-27

Week 5: Chiefs vs. Raiders (MNF)

Eric Hartline-USA TODAY Sports

I think there will be a bit of an adjustment period for Raiders head coach Josh McDaniels, who enters his second stint as an NFL head coach. I suspect he’ll be more successful in this tenure with the Raiders than he was with the Broncos in 2009-2010, but he’ll also take his lumps along the way. An early-season loss to the Chiefs in prime-time feels like one of those lumps.

Prediction: Chiefs win 27-17

Week 6: Chiefs vs. Bills

Jamie Squire/Getty Images

A rematch of the most thrilling game from last year’s postseason. I suspect that Buffalo is going to be pretty amped up for this game, given the results during the divisional round. I feel that Buffalo will take the game at Arrowhead, especially being that it’s a short week for Kansas City. Expect a close, but high-scoring affair, with a lot of dramatics. Should they meet again in the playoffs, however, the results will be different.

Prediction: Bills win 37-34

Week 7: Chiefs at 49ers

Kim Klement-USA TODAY Sports

This marks the first rematch between the Chiefs and 49ers during the regular season since Super Bowl LIV. While both teams have changed considerably since then, I think the 49ers are going to look at this as an opportunity to exact some revenge. Whether they’re facing Trey Lance or Jimmy G, I think Kansas City will be physically and emotionally drained after losing a close game to the Bills the week prior. Men

Prediction: 49ers win 30-21

Week 8: BYE

Christian Petersen/Getty Images

This is the earliest bye week that the Chiefs have had since 2016 when they had a Week 5 bye week. I think it comes at the right time and gives them the perfect opportunity to recharge for Weeks 9-14, which look pretty tough on paper.

Prediction: Chiefs win the bye week

Week 9: Chiefs vs. Titans (SNF)

Christopher Hanewinckel-USA TODAY Sports

The Chiefs haven’t had much luck against the Titans in the regular season as of late, but this year could be different. Kansas City added a ton of pieces on the defensive side of the ball who play the game with incredible effort, toughness and poise. I suspect that’ll be the difference against a similarly tough Tennessee squad that wants to win in the trenches and on the ground. To this point, I don’t think the K.C. defense will have had a statement game, but this will be the one that puts the league on notice.

Prediction: Chiefs win 19-9

Week 10: Chiefs vs. Jaguars

Corey Perrine/Florida Times-Union

The Chiefs defeated Doug Pederson’s Eagles back in 2017, the year they went on to win the Super Bowl. While Andy Reid’s former pupil will be looking to get his first win against his teacher, I expect this matchup to go a lot like the previous affair, especially with this game taking place in the confines of GEHA Field at Arrowhead Stadium.

Prediction: Chiefs win 34-17

Week 11: Chiefs at Chargers

Gary A. Vasquez-USA TODAY Sports

I get the feeling that this could be the highest-scoring game of the season for Kansas City. The coaching staff in L.A. will have made some adjustments to handle the newness of the Chiefs’ offense. On the flip side, I expect the defense to have a tougher time defending the Chargers on the second go around. In the end, this one will come down to who has possession last.

Prediction: Chiefs win 42-37

Week 12: Chiefs vs. Rams

Kirby Lee-USA TODAY Sports

A match against the reigning Super Bowl champions? Yeah, this one is sure to be a good show. I’m not sure it elicits the same excitement that the ‘Monday Night Football’ game between these two teams in 2018 did, but I think it’ll be challenging for both squads nonetheless. In the end, I feel like Kansas City comes out on top at home.

Prediction: Chiefs win 31-24

Week 13: Chiefs at Bengals

Jay Biggerstaff-USA TODAY Sports

The Bengals beat the Chiefs twice last year, once at Paul Brown Stadium and once at GEHA Field at Arrowhead Stadium last season. I think if you look at the offseason in Kansas City, a lot of the changes they made on the defensive side of the ball are to help the team better matchup with Cincinnati. We’ll get a chance to see that in action this year.

Prediction: Chiefs win 37-31

Week 14: Chiefs at Broncos (SNF)

Ron Chenoy-USA TODAY Sports

Momentum can only carry you so far and I think Kansas City will stumble in the final leg of their toughest four-game stretch. The losing skid to the Chiefs has to come to an end at some point for the Broncos. Denver invested a lot in a veteran quarterback to ensure that happens this year. A prime-time atmosphere, late in the season, with injuries potentially coming into play — I think it’s highly likely that Russell Wilson and the Broncos snap the streak in this one.

Prediction: Broncos win 28-21

Week 15: Chiefs at Texans

Tommy Gilligan-USA TODAY Sports

Lovie Smith’s head-coaching record during the NFL’s regular season is barely above .500 during the course of his career. I expect the Texans to be better under his leadership, but not by much. Even with the Chiefs playing in enemy territory, look for this game to be a lopsided one. Kansas City gets right after a misstep against an AFC West rival.

Prediction: Chiefs win 31-17

Week 16: Chiefs vs. Seahawks

Ron Chenoy-USA TODAY Sports

The Seahawks are in the midst of a rebuild and their quarterback room currently consists of Drew Lock, Geno Smith and Jacob Eason. Need I say more?

Prediction: Chiefs win 38-7

Week 17: Chiefs vs. Broncos

Ron Chenoy-USA TODAY Sports

This game may very well determine the Broncos’ first season under new head coach Nathaniel Hackett. After winning the first match against Kansas City, I suspect there will be some overzealousness that shows in the penultimate game of the regular season. They’ll drop this game, likely due to a miscue or poor coaching decision.

Prediction: Chiefs win 31-24

Week 18: Chiefs at Raiders

Mark J. Rebilas-USA TODAY Sports

I suspect that Chad Henne will be getting the start or at least earning significant playing time in what could amount to a meaningless game late in the year. I also don’t think it will make much of a difference in the outcome of this game.

Prediction: Chiefs win 27-24.

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