Chris Sutton is making predictions for all 380 Premier League matches again this season, against a variety of guests.
Sutton's prediction: 3-0
Brighton's issue this season is the demands of European football on their squad - they beat Ajax in Amsterdam on Thursday night, so it will affect them again here.
Sheffield United will be buzzing after getting their first win of the season, against Wolves last week. Their gameplan here will be to sit in and try to frustrate the Seagulls, but I don't think they will keep Roberto de Zerbi's side quiet.
I wasn't sure whether to give the Blades a goal, because of Brighton's defensive record - they did not keep a clean sheet in any of their first 11 games of the season, so maybe this is the day they manage it.
Tom's prediction: 3-0
Joe's prediction: 2-0
Suggs' prediction: 1-0