The puck will drop at Consol Energy Center in Pittsburgh and is scheduled for 8 pm ET on Wednesday, November 13.
Pittsburgh won the last matchup 4-1, and the Flyers have lost four of their last six, but these teams have history that seems to always add intrigue to their contests. It was even rumored that they would play each other outdoors in the near future at Beaver Stadium.
The Penguins possess the league's co-leader in points in Sidney Crosby (23), but the Flyers' resident superstar, Claude Giroux, has just eight points on the season and hadn't scored a goal until Monday night.
Watch Pittsburgh Penguins vs. Philadelphia Flyers alongside all your social media on NBC Sports' Google+, NBC Sports on Facebook and @NBCSports on Twitter and visit ProHockeyTalk for extensive NHL coverage.