The Bears haven't been favored in too many games in recent seasons, but their Week 1 performance against the Green Bay Packers created some confidence in them, at least among Las Vegas oddsmakers.
A couple of books have the Bears by 3.5, and the over/under for the game is set at 43.5.
The Bears covered the spread against the Packers in their one-point loss, and the two teams finished just under the 47.5 point total.
Last week, Seattle lost to the Denver Broncos by three points, so Vegas is predicting a similar outcome for their second game.
Both the Bears and Seahawks were sloppy at times in their season opener, which could lead to some unpredictable football on Monday night.
It took a miraculous Aaron Rodgers comeback for Chicago to lose last week, and now the Bears' defense will face another clutch, mobile quarterback in Russell Wilson looking to avenge a Week 1 loss of his own.