Both teams have already secured the passage to the last-16 with top spot already wrapped up by the Bundesliga champions.
Jose Mourinho looks set to rest some of his more established first teamers with some of the club’s younger rising stars set to get a chance to shine.
Bayern infamously ran out 7-2 winners the last time the two met earlier in the group stage.
Here’s everything you need to know:
When is the match?
The match takes place on Wednesday December 11 with kick-off at 8pm in the UK.
What TV channel is it on?
The match will be broadcast on BT Sport 2.
It can also be streamed live by subscribers for free via the BT Sport website.
What’s the team news?
Hugo Lloris and Ben Davies are long-term absentees for Tottenham with Harry Winks and Tanguy Ndombele doubtful. Harry Kane could also be rested with Spurs’ progression to the last-16 already secure.
Corentin Tolisso and Jerome Boateng are both expected to be passed fit for the hosts.
Bayern Munich: Ulreich; Pavard, Boateng, Martinez, Davies; Kimmich, Tolisso, Coutinho; Coman, Gnabry, Lewandowski
Tottenham: Gazzaniga; Walker-Peters, Foyth, Tanganga, Rose; Skipp, Dier, Eriksen; Lucas, Sessegnon, Parrott
Who’s going to win?
Bayern Munich: 1/3
It’s a big test for Tottenham’s youngsters and while youthful exuberance may give them an outside chance of getting a result on the road Bayern’s extra experience at this level should prove enough. Bayern 3-1 Spurs