Like everyone in the league, the Jaguars' Calais Campbell knows what he willingly signed up for – and is paid handsomely to do. That doesn't mean the news doesn't hit like a punch to the gut.
Eventually it's the future in the United States (even outside the Las Vegas Raiders) although when that occurs remains the multibillion-dollar question.
A CTE diagnosis this significant comes as not just a surprise, but a chilling moment for a sport that is trying everything to both make the game safer and convince young athletes, and their parents, that it is worth playing.
King's landmark victory over Bobby Riggs was one for the ages, but her accomplishment was driven by something more than sports.
The defense was supposed to be strong and stingy, but too often, particularly against the Pittsburghs and New Englands of the league, it wasn't. Now maybe it's back.
"If I give them a show, I think they are going to want my jersey," Fournette said. "I might be the biggest player there."
Jim Harbaugh made his visit in 2013. Now it's the older brother's turn as he faces the same opponent.
Jacksonville still offers its charms, especially in times like this that it can be a benefit, when the small market, we're-all-in-this-together vibe, takes over.