The true-crime series takes an in-depth look at the murder of Odin Lloyd in 2013 and subsequent arrest, trial and conviction of NFL star Hernandez.
At the time of the murder, the American football star had signed a five-year $40 million (almost £31 million) contract with the New England Patriots, making the story headline news around the world.
The three-part Netflix series features trial footage, interviews with people close to the case and calls and letters from the NFL player while he was behind bars, before he took his own life.
Many of the phone calls were to Ms Jenkins which has thrust her back into the public eye.
Taking to social media, the mother of two - who had a daughter with Hernandez - wrote: "I wanted to let all of you sweet, sweet souls know I have to tried to read every message sent on IG [Instagram] and through email (positive and negative).
"The amount of support and positive energy is again unreal! I'm sure you will understand how imperative it is to take some time away from social media."
Ms Jenkins stood by the New England Patriots star throughout his trial, during his incarceration and following his 2017 death.
A post shared by Shayanna Jenkins - Hernandez (@shayjhernandez) on Jan 16, 2020 at 8:57am PST
She also was present at a second trial regarding two murders unrelated to Mr Lloyd’s which Hernandez was acquitted of.
Not everyone has responded well to the documentary and Hernandez's lawyer, Jose Baez, took to Instagram to slam the edit.
“I don't give a damn about what some lame a** documentary has to say about Aaron,” he said on Instagram.
“I knew him, they did not and while he was far from perfect, they are not even close to the truth.
I don’t give a damn about what some lame ass documentary has to say about Aaron. I knew him, they did not and while he was far from perfect, they are not even close to the truth. People have no idea how documentaries are made, the truth is usually found on the cutting room floor. These producers lied directly to my face, so I don’t expect their money making scheme to be much better. #ripchico #baezlawfirm #aaronhernandez
A post shared by Baez Law Firm (@baezlawfirm) on Jan 15, 2020 at 6:37am PST
“People have no idea how documentaries are made, the truth is usually found on the cutting room floor. These producers lied directly to my face, so I don't expect their money-making scheme to be much better."
Killer Inside: The Mind of Aaron Hernandez is available on Netflix now.