The team will face the Cardinals for the second time in three weeks in Week 11. After failing to sack Arizona quarterback Kyler Murray in the first meeting, Nick Bosa will try to do better the second time around.
Murray has been sacked 31 times, which ranks as the third-most in the league. San Francisco, on the other hand, ranks second in the NFL in total sacks (35) and yards allowed per game (251.6).
Here is how NFL writers across the league see the 49ers-Cardinals game shaking out:
Caesars: SF -480
Consensus: SF -500
Westgate: SF -550
Wynn: SF -550
49ers-Cardinals odds, predictions: Betting lines, picks for NFL Week 11 game originally appeared on NBC Sports Bay Area