Julysses Nobles led Jackson State (1-4) with 23 points while Treshawn Bolden added 14.
Wyoming took its largest lead at 52-36 following a technical foul on Jackson State coach Wayne Brent, but the Tigers made it close down the stretch, helped by a spate of Cowboy turnovers. Nobles' 3-point play drew Jackson State within 59-54 at the 7:13 mark. Wyoming made 10 of 10 free throws in the final minutes to hold on.
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