The A's look to extend their home winning streak to seven games while trying to hand the White Sox a fifth consecutive defeat Saturday.
Bartolo Colon tossed a five-hitter and Josh Reddick came off the disabled list to deliver a tiebreaking double as Oakland (32-24) scored all its runs in the eighth inning for a 3-0 win over Chicago on Friday. Coco Crisp added a two-run single to help the A's win for the 12th time in 14 games.
Oakland has not won seven straight at home since a 10-game run Aug. 11-Sept. 1, 2006.
Reddick, on the DL since May 8 with a sprained wrist, hit the second of consecutive doubles in the eighth inning. The A's managed two hits through seven before recording three in the eighth.
After setting career highs with 32 homers and 85 RBIs for the A's last season, Reddick was batting .158 with a home run and 15 RBIs in 30 games this year. He simply wants to contribute as much as he can and help Oakland continue its current success.
"I just hope I don't screw anything up,'' he said. "Those guys have done a heck of a job without me, on the DL and with me not playing and producing. I just hope I can come in here and jump on this train and keep it going. Not necessarily driving it, just jump on the back cart and keep it going.''
Crisp, meanwhile, has hit .349 (15 for 43) with eight RBIs in 11 games to raise his average from .257 to .283.
Scheduled Oakland starter Dan Straily (3-2, 5.08 ERA) was 0-2 with an 8.84 ERA in his first previous four starts, but has allowed a run and six hits over 13 innings to win two in a row. He gave up that run and four hits over six in Monday's 4-1 victory over San Francisco.
"I worked a lot quicker. Really, that's the pitcher I am,'' he said. "I was finally able to break through that and be myself - work quick, fill up the strike zone.
"I've always said I'm a strike thrower and not a strikeout pitcher. That's what I truly believe.''
This will be the right-hander's first appearance against the White Sox (24-28), who have been outscored 27-6 and shut out twice while dropping four straight since reaching .500 for the first time since April 10.
''It seems like it's kind of been a theme this year - our pitching's kept us in pretty much every ballgame except a few all year, and we're just not able to get anything going offensively,'' Adam Dunn said. ''We've got to find a way to get on base somehow, someway and start creating things.''
Right fielder Alex Rios is 2 for 23 in six contests since he batted .375 during an 18-game hitting streak.
Chicago's Jose Quintana (3-2, 3.75) takes the mound after he allowed four runs for the second time in three starts. On Monday, he lasted six innings as his teammates managed two hits during a 7-0 loss to the Cubs.
The left-hander gave up six hits and struck out 14 over 13 2-3 scoreless innings to go 1-0 in his first two road starts of 2013, but has yielded 11 runs and 20 hits over 16 2-3 frames while not factoring in the decision of his last three away from home.
Quintana has never faced Oakland, which has won eight of 12 at home from the White Sox.
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