Marco van Basten has told Heerenveen he will leave the Eredivisie club when his contract expires at the end of the season.
The former Netherlands striker took charge ahead of the 2012-13 campaign, leading the club to an eighth-placed finish in his first year at the helm.
Heerenveen currently sits fifth in the Dutch top flight, but Van Basten has revealed he will walk away in May.
"Coach Marco van Basten has informed Heerenveen that he has decided not to renew his contract with the club," read a statement on Heerenveen's official website.
"The board regrets his decision, but has to respect this course."
The 49-year-old started his coaching career with Ajax's reserve side before spending four years as Netherlands boss and a single season at the Godenzonen helm, prior to his current position.