Maduka also had 10 rebounds, as he and Clarkson matched their season scoring highs.
The Golden Hurricane (9-9, 2-2 Conference USA) raced to a 22-4 advantage behind 11 points by Clarkson, who scored 19 by halftime.
After making two of their first 13 shots, the Pirates (9-7, 0-3) made eight of their next 10 and trailed 40-33 at halftime.
East Carolina continued to come back, led by Miguel Paul's 13 points, all In the second half. His 3-pointer made it 67-65, but Maduka's three-point play made it 70-65 with 44 seconds left.
With a chance to tie, the Pirates missed two 3-pointers in the final 24 seconds.
Darrius Morrow scored 18 points for East Carolina and Maurice Kemp had 10 points and 10 rebounds.
- Sports & Recreation
- Sports & Recreation/Basketball
- East Carolina