England defender John Terry will miss Tuesday's World Cup qualifying clash with Ukraine after failing to recover from an injury picked up in the 5-0 win over Moldova.
The Chelsea skipper sustained a knock on his ankle midway through the second half of Friday's game but remained on the pitch as Roy Hodgson had already made his three permitted substitutes.
Terry's club-mate Gary Cahill is his likely replacement, although Everton defender Phil Jagielka is also a candidate to partner Joleon Lescott at the heart of England's defense.
Hodgson has already lost first-choice left back Ashley Cole for the clash with Ukraine as well as Sunderland attacker Adam Johnson and Manchester United's Wayne Rooney.
Manchester City and England midfielder James Milner admitted that losing a player of Terry's quality was a blow, but insisted the strength in depth at the Three Lions' disposal would mean his loss wouldn't be felt too hard.
He told reporters: "Obviously JT is a top player and will be tough to replace, but we've got a number of top candidates who can step right in, so it shouldn't be too much of a problem."
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