Braylon Edwards made the Seahawks' 53-man roster, with the team waiving former draft picks Deon Butler and Kris Durham amid a flurry of moves to reach Friday's roster limit.
Charly Martin also made the receiving corps for now, with promising speedster Ricardo Lockette let go.
Among the notable names of players waived was quarterback Josh Portis, meaning the team will open the season with only two quarterbacks in Russell Wilson and Matt Flynn. Cornerback Phillip Adams, defensive end Pierre Allen, offensive lineman Paul Fanaika and linebacker Allen Bradford were also waived.
Linebacker Korey Toomer was the only rookie draft pick not to make the roster.
The undrafted rookies waived were: offensive linemen Kris O'Dowd and Rishaw Johnson, tight end Sean McGrath, wide receivers Jermaine Kearse and Lavasier Tuinei, linebacker Kyle Knox, defensive end Cordarro Law and safety DeShawn Shead.
Cornerback Walter Thurmond will begin the season on the physically unable to perform list and must six out at least the first six weeks of the season, although 2011 first-round pick James Carpenter was activated and added to the roster.
Tight end Cooper Helfet and running back Vai Taua were placed on waived/injured, while veteran linebacker Matt McCoy was placed on injured reserve.