The Denver Broncos will be without wide receiver Wes Welker for their AFC West matchup with the San Diego Chargers on Thursday night.
Welker will miss the game because of a concussion that he suffered in Sunday's 51-28 win over the Tennessee Titans on a hit by safety George Wilson, the Broncos announced Wednesday.
It was Welker's second concussion within the past month. The first came in a game against the Kansas City Chiefs in Week 11, but he returned the following week to play against New England.
Because of the short practice week resulting from the Thursday night game, Welker had less time to pass the NFL's concussion protocol tests for clearance to play against the Chargers.
The 32-year-old Welker is the Broncos' second-leading receiver this season with 73 catches for 778 yards and 10 touchdowns, including a scoring reception and 61 yards against the Titans on Sunday.
The Broncos (11-2) enter the game against the Chargers (6-7) with a one-game lead over the Kansas City Chiefs in the AFC West. The Chargers remain in contention for a wild-card berth.