SAN FRANCISCO -- Mike Leake helped his own cause with a career-best three hits, and he scattered 12 hits over six-plus innings on the mound Wednesday, lifting the Cincinnati Reds to an 8-3 win over San Francisco Giants.
The Reds trounced the Giants three times in the four-game series.
Joey Votto, Brandon Phillips, Jay Bruce and Devin Mesoraco had two hits apiece as the Reds completed a demolition of the defending World Series champions by outscoring them 31-11 over three days that included a doubleheader split Tuesday.
The Reds won six of seven games against the Giants in the season series, outscoring the team that eliminated them from the 2012 playoffs 45-14.
Leake (10-4) stranded 10 Giants baserunners while running his career record against San Francisco to 5-1. He allowed one run, walked two and struck out two.
Right-hander Sam LeCure relieved Leake with the bases loaded and no outs in the seventh and stranded three more Giants. One of the outs came when he got pinch hitter Buster Posey to ground to first baseman Votto, who threw for a forceout at the plate.
Leake, who had totaled just five hits in 41 at-bats in his first 19 starts, raised his average from .122 to .178 with his fourth- and seventh-inning singles and fifth-inning double. The extra-base hit was his first of the season.
The Reds, who were completing the first leg on an 11-game road trip, broke the game open early with a three-run third inning and a two-run fourth against Chad Gaudin (4-2). The Giants right-hander had been unbeaten in seven starts this season.
Mesoraco capped the third with a run-scoring single, his first of two RBIs in the game. He had seven RBIs in the series, going 8-for-16.
Pablo Sandoval and Hunter Pence, batting third and fourth in a starting lineup that did not include Posey, combined for seven of the Giants' 15 hits.
Pence went 5-for-5, matching a career high for hits last accomplished for the Houston Astros in May 2008. Sandoval's two hits included a two-run double in the eighth inning that helped make the final score respectable.
The Giants, who out-hit the Reds 15-13, stranded 15 baserunners in all.
Marco Scutaro, who scored two runs, and Brandon Crawford also had two-hit games for the Giants, who were out-hit 55-39 in the high-scoring series.
Gaudin, who had allowed a total of just two runs in his previous four starts, couldn't make it out of the fourth inning. He issued a season-worst five walks, which combined with seven hits produced six runs.
All nine batters in the Reds' starting lineup reached base at least once against Gaudin.
NOTES: Giants pitching coach Dave Righetti had elbow surgery Wednesday and missed the series finale. He's expected to rejoin the team Friday. ... Giants RHP Ryan Vogelsong made his first start Tuesday since breaking his right (pitching) hand May 20, throwing two shutout innings for Class A San Jose. The 2011 All-Star is scheduled to extend to 35 pitches in a start for Triple-A Fresno on Friday. ... Reds LF Ryan Ludwick (Class A Dayton) and Giants INF Joaquin Arias (Fresno) began injury-rehab assignments Wednesday. ... As expected, both starting pitchers from the first game of Tuesday's doubleheader -- Reds LHP Tony Cingrani and Giants LHP Eric Surkamp -- were sent back to the minors. The Reds plan to recall Cingrani to start Sunday in Los Angeles. ... The Reds open a four-game series against the Dodgers on Thursday night. The Giants get a day off before hosting the Chicago Cubs in a three-game series that begins Friday.