He replaces New York Yankees starter Masahiro Tanaka, who was placed on the disabled list on Wednesday.
It's the first major league All-Star selection for Uehara. He was honored for the Yomiuri Giants in Japan eight times.
The 39-year-old closer is 4-2 with 18 saves and a 1.30 ERA this season.
Uehara joins left-hander Jon Lester as the Boston representatives for next week's game in Minneapolis.
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- Boston Red Sox
- Koji Uehara
- New York Yankees