Bayern Munich will take on Manchester United in the standout tie of the Champions League quarterfinals.
Pep Guardiola's men are keen to become the first club to successfully defend the title, but will have to deal with the champions of England first, with the first leg scheduled to take place at Old Trafford.
Elsewhere, Real Madrid will be gunning for revenge against Borussia Dortmund after last year's elimination in the semifinals, while Ligue 1 leader Paris Saint-Germain meets the Premier League's table-topper, Chelsea, as the French outfit aims to improve on last year's run to the last eight.
Finally, Barcelona has been paired with Atletico Madrid, which will be a particularly interesting fixture given Diego Simeone's men caused the Catalans all kinds of trouble in their domestic dust-ups in the Supercopa de Espana and La Liga earlier this season.
The first legs will take place on April 1 and 2, with the second legs scheduled for April 8 and 9.
The draw for the semifinals will be held on April 11, while the tournament concludes at Estadio do Sport Lisboa e Benfica on May 24.