Clyne, Yoshida, Hooiveld, Fox
Lallana, Ramirez, Rodriguez
Fabio, Samba, Hill, Traore
Townsend, Taarabt, Mackie
Southampton is sweating on the fitness of Luke Shaw (ankle) after the young left back picked up a knock against Newcastle last weekend.
The host will also be closely monitoring Guly Do Prado (knee), with the striker expected to take a place on the bench after returning from injury.
QPR, meanwhile, is unlikely to be able to call on Bobby Zamora (ankle) and Esteban Granero (ankle), after the duo picked up injuries in the recent 2-0 defeat to Manchester United.
Loic Remy could be set to start after coming on in place of Zamora early in the second half of that game, while Shaun Derry should replace Granero.