EAST RUTHERFORD, N.J. -- Peyton Manning's Denver Broncos are 2-0 this season and big brother is now undefeated in three head-to-head games against Eli Manning and the New York Giants.
Denver's offense shook off a goal-line fumble by running back Montee Ball to turn a 10-9 halftime lead into a second convincing victory, 41-23, backing up their Week 1 home win over the Baltimore Ravens.
The Giants, who had five turnovers in a loss at Dallas last week, continued to struggling running the ball, converting on third down, and failing to convert in the red zone. Their first-half scoring consisted of three field goals by kicker Josh Brown.
"We knew it was going to be tough," said Broncos head coach John Fox. "They battled us hard and we made some adjustments at halftime and we were able to get some takeaways early and kind of shift the game a bit."
Peyton Manning passed for 307 yards with two touchdowns and running back Knowshon Moreno added a pair of rushing scores for the Broncos, who intercepted Eli Manning four times.
The Giants had their opportunities.
After Denver took the lead early in the second quarter on a 20-yard touchdown run by Moreno, Eli Manning connected with tight end Brandon Myers, who had a wide open field in front of him. Myers lost his footing and fell to the ground, ending up with a 27-yard reception on a drive that ended up stalling at the Broncos' 6.
After the Broncos took the 10-9 lead at the half on Matt Prater's 42-yard field goal Eli Manning drove the team downfield but a pass intended for wide receiver Hakeem Nicks was picked off by cornerback Dominique Rodgers-Cromartie in the end zone.
The Giants and Broncos exchanged touchdowns in the third quarter -- Denver had a 2-yard strike to receiver Wes Welker while New York managed a 1-yard run by running back Brandon Jacobs to make it 17-16.
Denver began to pull away with 21 unanswered points, beginning with a 25-yard touchdown run by Moreno, the Belford, N.J. native, whose score was his second of the game to give him his first multiple rushing touchdown performance since 2010.
"That was a big game for him playing in his hometown somewhat," said Peyton Manning. "I thought he ran hard and it really opened up some things in the second half in the passing game."
Moreno's second rushing touchdown was followed by an 11-yard touchdown pass from Manning to tight end Julius Thomas and then an 81-yard touchdown return by Broncos' punt returner Trindon Holliday to give Denver a 38-16 lead.
"We talked about not punting the game down the middle of the field to this guy and that's all it was, down the middle of the field," Coughlin said.
The Giants came up with a late score when Eli Manning found running back Da'Rel Scott open over the middle for a 23-yard touchdown reception to cap a four-play, 71-yard scoring drive that made it 38-23.
Denver added the finishing touches on its big win on Prater's second field goal of the day, a 47-yarder.
The Broncos' win gave Peyton's teams a 3-0 advantage over Eli's teams in the Manning Bowl, but more importantly, it improved Denver's record to 2-0 while the Giants dropped to 0-2 for the first time since the 2007 season.
"We've been 0-2 before, we have dug ourselves into a hole before and fought our way out of it and when we did it, it was as a team," said Coughlin. "The performance level has to come up."
The Giants are on the road next week to face the Carolina Panthers while Denver will host the Oakland Raiders at home on Monday night.
Notes: The Giants had 24 rushing yards between Jacobs and second-year running back David Wilson, who started despite fumbling twice last week. Wilson also returned kickoffs. ... The win was Denver's seventh consecutive regular-season road game victory. It was also the Broncos' 13th consecutive regular-season win, which is the longest active streak in NFL, and the second longest such streak in team history. Denver is just one game away from tying their longest regular-season win streak, which was established in 1997-1998. ... The Giants fell to 2-2 in MetLife home openers and are now 49-35-5 overall in home openers. ... Peyton Manning became the third quarterback in NFL history to top 60,000 passing yards, joining former Miami quarterback Dan Marino and former green Bay quarterback Brett Favre in that category. Manning joined that elite group on his team's ninth play from scrimmage on its opening possession, becoming the fastest of the three to accomplish that feat by doing so in 7,841 attempts.